Blindness due to vitamin A deficiency

  • Vinodini Reddy


Vitamin A deficiency is a major public health problem in most developing countries, contributing to a considerable proportion of preventable blindness in young children. The condition is particularly serious during the post-weaning stage in socially and economically deprived areas and is frequently associated with protein-energy malnutrition. The prevalence of vitamin A deficiency is very high in the countries of South East Asia. It is estimated that in India alone, there may be over one million cases of blindness arising from vitamin A deficiency. In human terms, the cost of blindness is incalculable. In economic terms, it is staggering. And yet this condition has not received the attention it deserves from public health workers. This is most unfortunate since vitamin A deficiency is easily preventable within the current economic framework of most developing countries.


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  1. Belavady, B., Gopalan, C. (1959). Ind. J. med. Res., 47, 234.Google Scholar
  2. Brenner, S., Roberts, L. J. (1943). Arch. Int. Med., 71, 474.CrossRefGoogle Scholar
  3. FAO/WHO (1967). Tech. Rep. Series No. 362.Google Scholar
  4. Gopalan, C., Rao, N. (1968). Indian Council of Medical Research. Spec. rep. series No. 60.Google Scholar
  5. Ingenbleek, Y., Schrieck, H., De Nayer, P., De Vissher, M. (1975). Metabolism, 24, 633.CrossRefGoogle Scholar
  6. lyengar, L., Apte, S. V. (1972). Br. J. Nutr., 27, 313.CrossRefGoogle Scholar
  7. Lala, V., Reddy, V. (1970). Am. J. Clin. Nutr., 23, 110.Google Scholar
  8. McCord, A. B., Katsampes, C. P., Martin, F. J., Ulstrom, R. A., Tully, R. H., Keenan, A. J. (1948). Pediatrics, 2, 652.Google Scholar
  9. Mejia, L. A., Hodges, R. E., Mohanram, M., Rucker, R. B., Arroyave, G. (1976). Fed. Proc., 35, 663.Google Scholar
  10. Mohanram, M., Kulkarni, K. A., Reddy, V. (1977). Intern. J. Vit. Nutr. Res., 47, 389.Google Scholar
  11. Muhilal, H., Glover, J. (1974). Br. J. Nutr., 32, 549.CrossRefGoogle Scholar
  12. N.I.H. (1963). Manual for nutrition surveys. Interdepartmental committee on nutrition for national defence. 2nd Ed. N. I. H. Bethesda, Maryland.Google Scholar
  13. National Institute of Nutrition (1972). Annual Report. Hyderabad.Google Scholar
  14. PAHO (1970). Report of a technical group meeting. Hypovitaminosis A in the Americas.Google Scholar
  15. Pereira, S. M., Begum, A., Isaac, T., Dumm, M. E. (1967). Am. J. Clin. Nutr., 20, 297.Google Scholar
  16. Rao, N. P., Singh, D., Swaminathan, M. C. (1969). Ind. Jour. med. Res., 57, 2132.Google Scholar
  17. Rao, N. P., Rao, N. (1970). Am. J. Clin. Nutr., 23, 110.Google Scholar
  18. Reddy, V., Mohanram, M., Raghuramulu, N. (1979). Acta Peadiatr. Scand., 68, 65.CrossRefGoogle Scholar
  19. Reddy, V., Sivakumar, B. (1972). Indian Pediat., 9, 307.Google Scholar
  20. Reddy, V., Srikantia, S. C. (1966). Am. J. Clin. Nutr., 18, 105.Google Scholar
  21. Sauter, J. (1976). Xerophthalmia and measles in Kenya. Drukkerij van Denderen B. V.Google Scholar
  22. Gorningen. Sivakumar, B., Reddy, V. (1972). Br. J. Nutr., 27, 299.CrossRefGoogle Scholar
  23. Sivakumar, B., Reddy, V. (1975). J. trop. Med. Hyg., 78, 114.Google Scholar
  24. Smith, F. R., Goodman, D. S., Zaklama, M. S., Gabr, M. K., EI Maraghy, S., Patwzrdhan, V. N. (1973). Am. J. Clin. Nutr., 26, 973.Google Scholar
  25. Srikantia, S. G., Belavady, B. (1961). Ind. J. Med. Res., 49, 109.Google Scholar
  26. Srikantia, S. G., Reddy, V. (1970). Am. J. Clin. Nutr., 23, 114.Google Scholar
  27. Swaminathan, M. C., Susheela, T. P., Thimmayamma, B. V. S. (1970). Am. J. Clin. Nutr., 23, 119.Google Scholar
  28. Swaminathan, M. C. (1971). Proc. First Asian Congress, Hyderabad, p. 696.Google Scholar
  29. Venkatachalam, P. S., Belavady, B., Gopalan, C. (1962). J. Pediat., 61, 262.CrossRefGoogle Scholar
  30. W.H.O. (1976). Tech. Rep. Series No. 590, Vitamin A deficiency and xerophthalmia.Google Scholar
  31. Wolf, G., Varandani, P. T. (1960). Biochem. Biophys. Acta., 43, 501.CrossRefGoogle Scholar

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© H. M. Wallace and G. J. Ebrahim 1981

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  • Vinodini Reddy

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