Abstract
In the grafting or serial passage of biological material there is always a risk that adventitious infectious organisms will be transmitted alongside the material of interest. For instance, the presence of tubercle bacilli used to be a common hazard of handling human tumour biopsies or autopsies, and the acquisition of serially transplanted mouse tumours has on occasion introduced murine hepatitis virus or Sendai virus into mouse colonies. Another cause for concern peculiar to heterotransplantation is the infection of a xenograft by a xenotropic retrovirus present in the host animal, and that is what I shall discuss here.
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© 1980 The Medical Research Council
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Weiss, R.A. (1980). Viral contaminants of xenografts. In: Sparrow, S. (eds) Immunodeficient Animals for Cancer Research. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-05014-7_20
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DOI: https://doi.org/10.1007/978-1-349-05014-7_20
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