Abstract
The structure of DNA in its functional state in cells is modified by protein binding and the introduction of superhelix density. Whilst this is probably true for most natural DNA molecules, it is especially so for eukaryotic DNA, where an at least equal weight of protein serves to contract about one metre of nucleic acid by approximately five orders of magnitude. Typically, a human somatic cell contains about one thousand times the amount of DNA present in prokaryotic cells, where it is condensed into a nucleus of diameter 5 µm whilst allowing access to the enzymes involved in all aspects of nucleic acid metabolism. In eukaryotes discrete DNA molecules of between 104 to 106 kilobase pairs (Kb) in length are organised by protein into morphologically and genetically distinct units called chromosomes. The nucleoprotein material of which they are composed is generally called chromatin.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Adolph, K. W., Cheng, S. M. and Laemmli, U. K. (1977). Cell, 12, 805.
Altenburger, W., Hörz, W. and Zachau, H. G. (1976). Nature, Lond., 264, 517.
Arnott, S. and Hukins, D. W. L. (1973). J. molec. Biol., 81, 93.
Bak, A. L., Zeuthen, J. and Crick, F. H. C. (1977). Proc. natn. Acad. Sci., U.S.A., 74, 1595.
Baldwin, J. P., Boseley, P. G. and Bradbury, E. M. (1975). Nature, Lond., 253, 245.
Baudy, P. and Bram, S. (1978). Nucl. Acids Res., 5, 3697.
Baudy, P., Bram, S., Vastel, D. and Lepault, J. (1976). Biochem. biophys. Res. Commun., 72, 176.
Beard, P. (1978). Cell, 15, 955.
Benyajati, C. and Worcel, A. (1976). Cell, 9, 393.
Berkowitz, E. M. and Doty, P. (1975). Proc. natn. Acad. Sci. U.S.A., 72, 3328.
Billett, M. A. (1979). Biochem. Soc. Trans., 7, 381.
Bina-Stein, M. and Simpson, R. T. (1977). Cell, 11, 609.
Bloom, K. S. and Anderson, J. N. (1978). Cell, 15, 141.
Böhm, L., Hayashi, H., Cary, P. D., Moss, T., Crane-Robinson, C. and Bradbury, E. M. (1977). Eur. J. Biochem., 77, 487.
Bradbury, E. M. and Crane-Robinson, C. (1971). In Histones and Nucleohistones (ed. D. Phillips), Plenum Press, New York, p. 85.
Bradbury, E. M., Molgaard, H. V., Stephens, R. M., Bolund, L. A. and Johns, E. M. (1972). Eur. J. Biochem., 31, 474.
Bram, S., Baudy, P., Lepault, J. and Hermann, D. (1977). Nucl. Acids Res., 4, 2275.
Bram, S. and Ris, H. (1971). J. molec. Biol., 55, 325.
Brandt, W. F., Böhm, L. and Von Holt, C. (1975). FEBS Lett., 51, 88.
Bryan, P. N., Wright, E. B., Hsie, M. H., Olins, A. L. and Olins, D. E. (1978). Nucl. Acids Res., 5, 3603.
Burgoyne, L. A., Mobbs, J. D. and Marshall, A. J. (1976). Nucl. Acids Res., 3, 3293.
Butt, T. R., Jump, D. B. and Smulson, M. E. (1979). Proc. natn. Acad. Sci. U.S.A., 76, 1628.
Camerini-Otero, R. D. and Felsenfeld, G. (1977). Nucl. Acids Res., 4, 1159.
Camerini-Otero, R. D., Sollner-Webb, B. and Felsenfeld, G. (1976). Cell, 8, 333.
Campbell, A. M., Briggs, R. C., Bird, R. E. and Hnilica, L. S. (1979). Nucl. Acids Res., 6, 205.
Campbell, A. M. and Cotter, R. I. (1976). FEBS Lett., 70, 209.
Campbell, A. M., Cotter, R. I. and Pardon, J. F. (1978). Nucl. Acids Res., 5, 1571.
Carpenter, B. G., Baldwin, J. P., Bradbury, E. M. and Ibel, K. (1976). Nucl. Acids Res., 3, 1739.
Cary, P. D., Moss, T. and Bradbury, E. M. (1978). Eur. J. Biochem., 89, 475.
Chambon, P. (1978). Cold Spring Harb. Symp. quant. Biol., 42, 1209.
Cheah, K. S. E. and Osborne, D. J. (1977). Biochem. J., 163, 141.
Chung, S.-Y., Hill, W. E. and Doty, P. (1978). Proc. natn. Acad. Sci. U.S.A., 75, 1680.
Coleman, J. E., Anderson, R. A., Ratcliffe, R. G. and Armitage, I. M. (1976). Biochemistry, 15, 5419.
Compton, J. L., Bellard, M. and Chambon, P. (1976). Proc. nain. Acad. Sei. U.S.A., 73, 4382.
Cook, I. and Brazell, P. (1975). J. Cell Sci., 19, 261.
Cotter, R. I. and Lilley, D. M. J. (1977). FEBS Lett., 82, 63.
Cotter, R. I., Pardon, J. F., Lilley, D. M. J. and Worcester, D. L. Submitted for publication.
Crick, F. H. C. (1976). Proc. nain. Acad. Sci. U.S.A., 73, 2639.
Crick, F. H. C. and Klug, A. (1975). Nature, Lond., 255, 530.
D’Anna, J. A. and Isenberg, I. (1974). Biochemistry, 13, 4992.
Davie, J. R. and Candido, E. P. M. (1978). Cell, 75, 3574.
Davies, H. G. and Haynes, M. E. (1975). J. Cell Sei., 17, 263.
Defer, J., Crepin, M., Terrioux, C., Kruh, J. and Gros, J. (1979). Nuel. Acids Res., 6, 953.
De Lange, R. J., Fambrough, D. M., Smith, E. L. and Bonner, J. (1969a). J. Biol. Chem., 244, 319.
De Lange, R. J., Fambrough, D. M., Smith, E. L. and Bonner, J. (1969b). J. Biol. Chem., 244, 5669.
De Lange, R. J., Hooper, J. A. and Smith, E. L. (1972). Proc. natn. Acad. Sci. U.S.A., 69, 882.
De Lange, R. J. and Smith, E. L. (1971). A. Rev. Biochem., 40, 279.
Dieterich, A. E., Axel, R. and Cantor, C. R. (1978). Cold Spring Harb. Symp. quant. Biol., 42, 199.
Dubochet, J. and Noll, M. (1978). Science, 202, 280.
Dupraw, E. J. (1970). DNA and Chromosomes, Holt, Rinehart and Winston, New York.
Eickbush, T. H. and Moudrianakis, E. N. (1978). Biochemistry, 17, 4955. Felsenfeld, G. (1978). Nature, bond., 257, 177.
Finch, J. T. and Klug, A. (1976). Proc. natn. Acad. Sci. U.S.A., 73, 1897.
Finch, J. T., Lutter, L. C., Rhodes, D., Brown, R. S., Rushton, B., Levitt, M. and Klug, A. (1977). Nature, Lond., 269, 29.
Flint, S. J. and Weintraub, H. M. (1977). Cell, 12, 783.
Foe, V. E., Wilkinson, L. E. and Laird, C. D. (1976). Cell, 9, 131.
Franke, W. W., Scheer, U., Trendelenburg, M. F., Spring, H. and Zentgraf, H. (1976). Cytobiologie, 13, 401.
Fuller, F. B. (1971). Proc. natn. Acad. Sei. U.S.A., 68, 815.
Garel, A. and Axel, R. (1976). Proc. nain. Acad. Sei. U.S.A., 73, 3966.
Garel, A. and Axel, R. (1978). Cold Spring Harb. Symp. quant. Biol., 42, 701.
Garel, A., Zolan, M. and Axel, R. (1977). Proc. natn. Acad. Sci. U.S.A., 74, 4867.
Germond, J. E., Hirt, B., Gross-Bellard, M. and Chambon, P. (1975). Proc. natn. Acad. Sci. U.S.A., 72, 1843.
Goodwin, G. H. and Johns, E. W. (1978). Biochem. biophys. Acta, 519, 279.
Gorenstein, D. G. and Kar, D. (1975). Biochem. biophys. Res. Commun., 65, 1073.
Gottesfeld, J. M. and Butler, P. J. G. (1977). Nucl. Acids Res., 4, 3155.
Gottesfeld, J. M. and Melton, D. A. (1978). Nature, Lond., 273, 317.
Gottesfeld, J. M., Murphy, R. F. and Bonner, J. (1975). Proc. nain. Acad. Sci. U.S.A., 72, 4404.
Griffith, J. D. and Christiansen, G. (1978). Cold Spring Harb. Symp. quant. Biol., 42, 215.
Guinier, A. and Fournet, G. (1955). In Small-angle Scattering of X-rays John Wiley, New York.
Harrison, S. C. and Kornberg, R. D. (1976). ICN Conference on Molecular Biology P. 7.
Hendrick, D., Tolstochev, P. and Randlett, D. (1977). Gene, 2, 147.
Hewish, D. R. and Burgoyne, L. A. (1973). Biochem. biophvs. Res. Commun., 52, 504.
Hildebrand, C. E. and Walters, R. A. (1976). Biochem. biophys. Res. Commun., 73, 157.
Hjelm, R. P., Kneale, G. G., Suau, P., Baldwin, J. P. and Bradbury, E. M. (1977). Cell, 10, 139.
Ibel, K. and Stuhrmann, H. B. (1975). J. molec. Biol., 93, 255.
Igo-Kemenes, T. and Zachau, H. G. (1978). Cold Spring Harb. Symp. quant. Biol., 42, 109.
Iwai, K., Ishikawa, K. and Hayashi, H. (1970). Nature, Lond., 226, 1056.
Jackson, V. and Chalkley, R. (1975). Biochem. biophys. Res. commun., 67, 1391.
Johns, E. W., Goodwin, G. H., Walker, J. M. and Sanders, C. (1975). In The Structure and Function of Chromatin, Ciba Foundation Symposium, vol. 28, p. 95.
Kallenbach, N. R., Appleby, D. W. and Bradley, C. H. (1978). Nature, Lond., 272, 134.
Keller, W. (1975). Proc. natn. Acad. Sci. U.S.A., 72, 4876.
Keller, W., Muller, U., Eicken, I., Wendel, I. and Zentgraf, H. (1978). Cold Spring Harb. Symp. quant. Biol., 42, 227.
Kelley, R. I. (1973). Biochem. biophvs. Res. Commun., 54, 1588.
Kievan, L. and Crothers, D. M. (1977). Nucl. Acids Res., 4, 4077.
Kornberg, R. D. (1974). Science, 184, 868.
Kornberg, R. D. (1977). A. Rev. Biochem., 46, 931.
Kornberg, R. D. and Thomas, J. O. (1974). Science, 184, 865.
Kuo, M. T., Sahasrabuddhe, C. G. and Saunders, G. F. (1976). Proc. natn. Acad. Sci. U.S.A., 73, 1572.
Lacy, E. and Axel, R. (1975). Proc. natn. Acad. Sci. U.S.A., 72, 3978.
Lakowicz, J. R. and Weber, G. (1973). Biochemistry, 12, 4171.
Lamb, M. M. and Daneholt, B. (1979). Cell, 17, 835.
Langmore, J. P. and Wooley, J. C. (1975). Proc. natn. Acad. Sci. U.S.A., 72, 2691.
Lau, A. F. and Ruddon, R. W. (1977). Exp. Cell Res., 107, 35.
Leffak, I. M., Grainger, R. and Weintraub, H. (1977). Cell, 12, 837.
Levine, Y. K., Birdsall, N. J. M., Lee, A. G. and Metcalf, J. C. (1972). Biochemistry, 11, 1416.
Levitt, M. (1978). Proc. natn. Acad. Sci. U.S.A., 75, 640.
Levy, A. and Jakob, K. M. (1978). Cell, 14, 259.
Levy-W., B. and Dixon, G. H. (1978a). Nucl. Acids Res., 5, 4155.
Levy-W., B. and Dixon, G. H. (1978b). Can. J. Biochem., 56, 480.
Lilley, D. M. J. (1977). In Molecular Spectroscopy (ed. A. R. West), Heyden, London, p. 96.
Lilley, D. M. J., Howarth, O. W., Clark, V. M., Pardon, J. F. and Richards, B. M. (1975). Biochemistry, 14, 4590.
Lilley, D. M. J., Howarth, O. W., Clark, V. M., Pardon, J. F. and Richards, B. M. (1976). FEBS Lett., 62, 7.
Lilley, D. M. J., Jacobs, M. F. and Houghton, M. (1979). Nucl. Acids Res., 7, 377.
Lilley, D. M. J. and Pardon, J. F. (1979). A. Rev. Genet., 13, 197.
Lilley, D. M. J., Pardon, J. F. and Richards, B. M. (1977). Biochemistry, 16, 2853.
Lilley, D. M. J., Richards, B. M., Pardon, J. F., Cotter, R. I. and Worcester, D. L. (1978). In Gene Expression, 11th FEBS Meeting, Copenhagen (ed. B. F. C. Clark), Pergamon Press, Oxford, New York, p. 213.
Lilley, D. M. J. and Tatchell, K. (1977). Nuel. Acids Res., 4, 2039.
Liu, L. F. and Wang, J. C. (1978). Cell, 15, 979.
Lohr, D., Corden, J., Tatchell, K., Kovacic, R. T. and Van Holde, K. E. (1977). Proc. natn. Acad. Sei. U.S.A., 74, 79.
Lohr, D., Kovacic, R. T. and Van Holde, K. E. (1977). Biochemistry, 16, 463.
Lohr, D., Tatchell, K. and Van Holde, K. E. (1977). Cell, 12, 829.
Lutter, L. C. (1977). J. molec. Biol., 117, 53.
Lutter, L. C. (1978). J. molec. Biol., 124, 391.
Lutter, L. C. (1979). Nucl. Acids Res., 6, 41.
Luzzati, V. and Nicolaieff, A. (1963). J. molec. Biol., 7, 142.
McKnight, S. L. and Millar, O. L. (1977). Cell, 12, 795.
Martinson, H. G., True, R. J. and Burch, J. B. E. (1979). Biochemistry, 18, 1082.
Mayfield, J. E., Serunian, L. A., Silver, L. M. and Elgin, S. C. R. (1978). Cell, 14, 539.
Millar, O. L. and Beatty, B. R. (1969). Science, 164, 955.
Mirzabekov, A. D., Sanko, D. F., Kolchinsky, A. M. and Melnikova, A. F. (1977). Eur. J. Biochern., 75, 379.
Mirzabekov, A. D., Shick, V. V., Belyaysky, A. V. and Bavykin, S. G. (1978). Proc. natn. Acad. Sci. U.S.A., 75, 4184.
Morris, N. R. (1976). Cell, 8, 357.
Moss, T., Cary, P. D., Abercrombie, B. D., Crane-Robinson, C. and Bradbury, E. M. (1976a). Eur. J. Biochem., 71, 337.
Moss, T., Cary, P. D., Crane-Robinson, C. and Bradbury, E. M. (1976b). Biochemistry, 15, 2261.
Moss, T., Stevens, R. M., Crane-Robinson, C. and Bradbury, E. M. (1977). Nucl. Acids Res., 4, 2477.
Murphy, R. F., Wallace, R. B. and Bonner, J. (1978). Proc. natn. Acad. Sei. U.S.A., 75, 5903.
Newrock, K. M., Alfageme, C. R., Nardi, R. V. and Cohen, L. H. (1978). Cold Spring Harb. Symp. quant. Biol., 42, 421.
Noll, M. (1974a). Nature, Lond., 251, 249.
Noll, M. (1974b). Nucl. Acids Res., 1, 1573.
Noll, M. (1977). J. molec. Biol., 116, 49.
Noll, M. and Kornberg, R. D. (1977). J. moles. Biol., 109, 393.
Noll, M., Thomas, J. O. and Kornberg, R. D. (1975). Science, 187, 1203.
Olins, A. L. (1978). Cold Spring Harb. Symp. quant. Biol., 42, 325.
Olins, A. L., Breillatt, J. P., Carlson, R. D., Senior, M. B., Wright, E. B. and Olins, D. E. (1977a). In The Molecular Biology of the Mammalian Genetic Apparatus, (ed. P. O. P. Ts’o), Elsevier/North Holland, Amsterdam, p. 211.
Olins, D. E., Bryan, P. N., Harrington, R. E., Hill, W. E. and Olins, A. L. (1977b). Nucl. Acids Res., 4, 1911.
Olins, A. L. and Olins, D. E. (1974). Science, 183, 330.
Oudet, P., Germond, J. E., Bellard, M., Spadafora, C. and Chambon, P. (1978). Phil. Trans. R. Soc. B., 283, 241.
Oudet, P., Gross-Bellard, M. and Chambon, P. (1975). Cell, 4, 281.
Palmiter, R. D., Mulvihill, E. R., McKnight, G. S. and Senear, A. W. (1978). Cold Spring Harb. Symp. quant. Biol., 42, 639.
Pardon, J. F., Cotter, R. I., Lilley, D. M. J., Worcester, D. L., Campbell, A. M., Wooley, J. C. and Richards, B. M. (1978). Cold Spring Harb. Symp. quant. Biol., 42, 11.
Pardon, J. F. and Richards, B. M. (1979). In The Cell Nucleus (ed. H. Busch), vol. 7, p. 37.
Pardon, J. F., Richards, B. M. and Cotter, R. I. (1974). Cold Spring Harb. Symp. quant. Biol., 38, 75.
Pardon, J. F. and Wilkins, M. H. F. (1972). J. molec. Biol., 68, 115.
Pardon, J. F., Worcester, D. L., Wooley, J. C., Cotter, R. I., Lilley, D. M. J. and Richards, B. M. (1977). Nucl. Acids Res., 4, 3199.
Pardon, J. F., Worcester, D. L., Wooley, J. C., Tatchell, K., Van Holde, K. E. and Richards, B. M. (1975). Nucl. Acids Res., 2, 2163.
Paulson, J. R. and Laemmli, U. K. (1977). Cell, 12, 817.
Pfeiffer, W., Hörz, W., Ig6-Kemenes, T. and Zachau, H. G. (1975). Nature, Lond., 258, 450.
Pinon, R. and Salts, Y. (1977). Proc. natn. Acad. Sci. U.S.A., 74, 2850.
Pooley, A. S., Pardon, J. F. and Richards, B. M. (1974). J. molec. Biol., 85, 533.
Porod, G. (1951). Kolloid Z., 2, 83.
Prunell, A. and Kornberg, R. D. (1978). Phil. Trans. R. Soc. B., 283, 269.
Renz, M., Nehis, P. and Hozier, J. (1977). Proc. natn. Acad. Sci. U.S.A., 74, 1879.
Riggs, M. G., Whittaker, R. G., Neumann, J. R. and Ingram, V. M. (1977). Nature, Loud., 268, 462.
Richards, B. M., Cotter, R. I., Lilley, D. M. J., Pardon, J. F., Wooley, J. C. and Worcester, D. L. (1976). Current Chromosome Research (eds. K. Jones and P. E. Brandham), North Holland, Amsterdam.
Richards, B. M. and Pardon, J. F. (1970). Exp. Cell Res., 62, 184.
Richards, B. M., Pardon, J. F., Lilley, D. M. J., Cotter, R. I., Wooley, J. C. and Worcester, D. L. (1977). Cell Biol. Int. Rep., 1, 107.
Riley, D. and Weintraub, H. (1978). Cell, 13, 281.
Ris, H. and Kubai, D. F. (1970). A. Rev. Genet., 4, 263.
Roark, D. E., Geoghegan, T. E. and Keller, G. H. (1974). Biochem. biophys. Res. Commun., 59, 542.
Sasisekharan, V., Pattabiraman, N. and Gupta, G. (1978). Proc. natn. Acad. Sci. U.S.A., 75, 4092.
Seale, R. L. (1975). Nature, Lond., 255, 247.
Seale, R. L. (1978). Proc. natn. Acad. Sci. U.S.A., 75, 2717.
Sealy, L. and Chalkley, R. (1978). Nucleic Acids Res., 5, 1863.
Sedat, J. and Manuelidis, L. (1978). Cold Spring Harb. Symp. quant. Biol., 42, 331.
Seligy, V. L. and Poon, N. H. (1978). Nucl. Acids Res., 5, 2233.
Shaw, B. R., Herman, T. M., Kovacic, R. T., Beaudreau, G. S. and Van Holde, K. E. (1976). Proc. natn. Acad. Sci. U.S.A., 73, 505.
Shaw, B. R. and Schmitz, K. S. (1976). Biochem. biophys. Res. Commun., 73, 224.
Simon, R. H., Camerini-Otero, R. D. and Felsenfeld, G. (1978). Nucl. Acids Res., 5, 4805.
Simpson, R. T. (1978). Cell, 13, 691.
Simpson, R. T. and Whitlock, J. P. (1976). Cell, 9, 347.
Sobell, H. M., Tsai, C., Gilbert, S. G., Jain, S. C. and Sakore, T. D. (1976). Proc. natn. Acad. Sci. U.S.A., 73, 3068.
Sollner-Webb, B. and Felsenfeld, G. (1977). Cell, 10, 537.
Sollner-Webb, B., Melchior, W. and Felsenfeld, G. (1978). Cell, 14, 611.
Spadafora, C., Bellard, M., Compton, J. L. and Chambon, P. (1976). FEBS Lett., 69, 281.
Sperling, L. and Tardieu, A. (1976). FEBS Lett., 64, 89.
Spiker, S. and Isenberg, I. (1978). Cold Spring Harb. Symp. quant. Biol., 42, 157.
Staynov, D. Z., Spencer, M., Allan, J. and Gould, H. J. (1979). Nature, Lond., 279, 263.
Stein, A., Bina-Stein, M. and Simpson, R. T. (1977). Proc. natn. Acad. Sci. U.S.A., 74, 2780.
Steinmetz, M., Streeck, R. E. and Zachau, H. G. (1975). Nature, Lond., 258, 447.
Stockley, P. G. and Thomas, J. O. (1979). FEBS Lett., 99, 129.
Stratling, W. H., Muller, U. and Zentgraf, H. (1978). Exp. Cell Res., 117, 301.
Suau, P., Kneale, G. G., Braddock, G. W., Baldwin, J. P. and Bradbury, E. M. (1977). Nucl. Acids Res., 4, 3769.
Sussman, J. L. and Trifonov, E. N. (1978). Proc. natn. Acad. Sci. U.S.A., 75, 103.
Tata, J. R. and Baker, B. (1978). J. molec. Biol., 118, 249.
Tatchell, K. and Van Holde, K. E. (1978). Proc. natn. Acad. Sci. U.S.A., 75, 3583.
Thoma, F. and Koller, T. (1977). Cell, 12, 101.
Thomas, G. J., Prescott, B. and Olins, D. E. (1977). Science, 197, 385.
Thomas, J. O. and Butler, P. J. G. (1977). J. molec. Biol., 116, 769.
Thomas, J. O. and Furber, V. (1976). FEBS Lett., 66, 274.
Thomas, J. O. and Kornberg, R. D. (1975). Proc. natn. Acad. Sci. U.S.A., 72, 2626.
Thomas, J. O. and Thompson, R. J. (1977). Cell, 10, 633.
Todd, R. D. and Garrard, W. T. (1977). J. Biol. Chem., 252, 4729.
Trifonov, E. N. and Bettecken, T. (1979). Biochemistry, 18, 454.
Tsanev, R. and Petrov, P. (1976). J. Microsc. Biol. Cell, 27, 11.
Van Der Westhuyzen, D. R. and Von Holt, C. (1971). FEBS Lett., 14, 333.
Van Holde, K. E., Sahasrabuddhe, C. G. and Shaw, B. R. (1974). Nucl. Acids Res., 1, 1579.
Van Holde, K. E. and Weischet, W. O. (1978). In The Cell Nucleus (ed. H. Busch), vol. IV, Academic Press, New York, p. 75.
Varshaysky, A. J. and Bakayev, V. V. (1975). Mol. Biol. Rep., 2, 247.
Varshaysky, A. J., Bakayev, V. V. and Georgiev, G. P. (1976). Nucl. Acids Res., 3, 477.
Vidali, G., Boffa, L. C. and Alifrey, V. G. (1977). Cell, 12, 409.
Vidali, G., Boffa, L. C., Bradbury, E. M and Alifrey, V. G. (1978). Proc. nain. Acad. Sci. U.S.A., 75, 2239.
Vinograd, J. and Lebowitz, J. (1966). J. gen. Physiol., 49, 103.
Von Holt, C., Strickland, W. N., Brandt, W. F. and Strickland, M. S. (1979). FEBS Lett., 100, 201.
Wang, J. C. (1978). Proc. natn. Acad. Sci. U.S.A., 76, 200.
Weintraub, H. and Groudine, M. (1976). Science, 193, 848.
Weintraub, H., Palter, K. and Van Lente, F. (1975). Cell, 6, 85.
Weintraub, H. and Van Lente, F. (1974). Proc. nain. Acad. Sci. U.S.A., 71, 4249.
Weintraub, H., Worcel, A. and Alberts, B. (1976). Cell, 9, 409.
Weisbrod, S. and Weintraub, H. (1979). Proc. natn. Acad. Sci. U.S.A., 76, 630.
Weischet, W. O., Tatchell, K., Van Holde, K. E. and Klump, H. (1978). Nucl. Acids Res., 5, 139.
Whitlock, J. P., Rushizky, G. W. and Simpson, R. T. (1977). J. Biol. Chem., 252, 3003.
Whitlock, J. P. and Simpson, R. T. (1977). J. Biol. Chem., 252, 6516.
Whitlock, J. P. and Stein, A. (1978). J. Biol. Chem., 253, 3857.
Wilkins, M. H. F., Zubay, G. and Wilson, H. R. (1959). J. molec. Biol., 1, 179.
Woodcock, C. L. F. (1973). J. Cell. Biol., 59, 368a.
Wooley, J. C. and Langmore, J. P. (1978). In Molecular Human Cytogenetics (eds. R. S. Sparkes, D. Comings and C. F. Fox), Academic Press, New York, p. 41.
Worcel, A. and Burgi, I. E. (1972). J. molec. Biol., 71, 127.
Worcel, A., Han, S. and Wong, M. L. (1978). Cell, 15, 969.
Wray, W., Mace, M., Daskal, Y. and Stubblefield, E. (1978). Cold Spring Harb. Symp. quant. Biol., 42, 361.
Zama, M., Bryan, P. N., Harrington, R. E., Olins, A. L. and Olins, D. E. (1978e). Cold Spring Harb. Symp. quant. Biol., 42, 31.
Zama, M., Olins, D. E., Prescott, B. and Thomas, G. J. (1978b). Nucl. Acids Res., 5, 3881.
Editor information
Editors and Affiliations
Copyright information
© 1981 The Contributors
About this chapter
Cite this chapter
Lilley, D.M.J. (1981). Eukaryotic chromatin. In: Neidle, S. (eds) Topics in Nucleic Acid Structure. Topics in Molecular and Structural Biology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-04691-1_7
Download citation
DOI: https://doi.org/10.1007/978-1-349-04691-1_7
Publisher Name: Palgrave Macmillan, London
Print ISBN: 978-1-349-04693-5
Online ISBN: 978-1-349-04691-1
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)