Mass Transfer Modelling for Membrane Oxygenators

  • W. J. DorsonJr.
Chapter
Part of the Strathclyde Bioengineering Seminars book series (KESE)

Summary

Theoretical analysis of O2 and CO2 transfer in membrane lung channels with streamline flow has been sufficiently developed to adequately predict experimental results. These methods are of great utility both for data interpretation, since generalised coordinates are used, and determining either deficiencies or benefits of a particular membrane lung design. Total bypass units, of necessity, must contain large permeable membrane surface areas unless a technique to augment respiratory gas transfer is employed. The verification and advantages of theoretical methods will be considered along with their extension to geometries which use secondary flows to increase the efficiency of O2 and CO2 exchange.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Benn, J. A. (1974). Carbon dioxide transfer from weak acids and blood: The effects of carbonic anhydrase and oxygen uptake on carbon dioxide transfer in an oxygenator. Ph.D. Thesis, Massachusetts Institute of Technology.Google Scholar
  2. Christianson, H. B. (1976). Secondary velocity effects relating to gas exchange with fluids flowing in helical tubular membranes. Ph.D.Thesis, Arizona State University.Google Scholar
  3. Dean, W. R. (1927). Note on the motion of fluid in a curved pipe. Phil. Mag., 4, 208.CrossRefGoogle Scholar
  4. Dorson, W. J., Jr. and Larsen, K. G. (1971). Secondary flows in membrane oxygenators. Adv. Cardiol., 6, 17.CrossRefGoogle Scholar
  5. Dorson, W. J., Jr., Larsen, K. G., Elgas, R. J. and Voorhees, M. E. (1971). Oxygen transfer to blood: Data and theory. Trans Amer. Soc. Artif. Int. Organs, 17, 309.Google Scholar
  6. Dorson, W. J., Jr. and Voorhees, M. (1974). Limiting models for the transfer of CO2 and 02 in membrane oxygenators. Trans. Amer. Soc. Artif Organs, 20, 219.Google Scholar
  7. Dorson, W. J., Jr. and Voorhees, M. E. (1976). Analysis of oxygen and carbon dioxide transfer in membrane lungs. In W. M. Zapol and J. Qvist (Eds.), Artificial Lungs for Acute Respiratory Failure, Hemisphere, Washington, D.C.Google Scholar
  8. Drinker, P. A., Bartlett, R. H., Bialer, R. M. and Noyes, B. S., Jr. (1969). Augmentation of membrane gas transfer by induced secondary flows. Surgery, 66, 775.PubMedGoogle Scholar
  9. Drinker, P. A. (1972). Progress in membrane oxygenator design. Anesthesiology, 37, 242.PubMedCrossRefGoogle Scholar
  10. Hill, J. D., Iatridis, A., O’Keefe, R. and Kitrilakis, S. (1974). Technique for achieving high gas exchange rates in membrane oxygenation. Trans. Amer. Soc. Artif Int. Organs, 20, 249.Google Scholar
  11. Larsen, K. G. (1971). Oxygen transfer to water and blood flowing in permeable helical tubes. Ph.D. Thesis, Arizona State University.Google Scholar
  12. Lightfoot, E. N. (1968). Low-order approximations for membrane blood oxygenators. Amer. Inst. Chem. Eng. J., 14, 669.CrossRefGoogle Scholar
  13. Voorhees, M. E. (1976). Mutual transfer of carbon dioxide and oxygen to and from blood flowing in macrochannel devices. Ph.D. Thesis, Arizona State University.Google Scholar
  14. Weissman, M. H. and Mockros, L. F. (1968). Gas transfer to blood flowing in coiled circular tubes. J. Engng. Mech. Div. Amer. Soc. Civ. Engrs., 94, 857.Google Scholar

Copyright information

© Bioengineering Unit, University of Strathclyde 1977

Authors and Affiliations

  • W. J. DorsonJr.

There are no affiliations available

Personalised recommendations