Removal of Bilirubin from the Blood of Jaundiced Infants

  • S. Sideman
  • L. Mor
  • I. Rousseau
  • J. M. Brandes
  • D. Ben-Arie
Chapter
Part of the Strathclyde Bioengineering Seminars book series (KESE)

Summary

Removal of bilirubin by haemoperfusion is suggested to replace exchange transfusion of blood of jaundiced infants. Anion exchangers, coated with biocompatible polymers, were tested in vitro with human blood for bilirubin binding capacity and blood compatibility. Dowex 1 × 2 coated with poly-HEMA and an acrylic polymer crosslinked with albumin removed 50 – 75% of the initial bilirubin in 2 – 3 h. Platelet count fell by some 25%. Additional work is still required to develop a small, efficient and safe haemoperfusion system.

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Copyright information

© Bioengineering Unit, University of Strathclyde 1977

Authors and Affiliations

  • S. Sideman
  • L. Mor
  • I. Rousseau
  • J. M. Brandes
  • D. Ben-Arie

There are no affiliations available

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