Summary
The use of bulky equipment in renal support has been unavoidable in the past because large volumes of dialysate fluid were required. In order to make the devices smaller and portable, the amount of dialysate fluid has to be reduced and used in conjunction with a sorbent or eliminated altogether.
The use of sorbents in dialysate regeneration, their use in haemoperfusion and their potential in hepatic assist are outlined. The problems of sorbent particle release and blood trauma remain as deterrents to their widespread chronic application. Systems are proposed which may combine haemodialysis and haemoperfusion in the treatment of renal and hepatic failure. It is suggested that future development in this area will be characterised by the advent of sorbent systems exhibiting characteristics more specific to the biological needs of particular applications.
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References
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© 1977 Bioengineering Unit, University of Strathclyde
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Nosé, Y., Malchesky, P.S. (1977). Sorbents in Therapeutic Medicine. In: Kenedi, R.M., Courtney, J.M., Gaylor, J.D.S., Gilchrist, T., Gerard, S.M. (eds) Artificial Organs. Strathclyde Bioengineering Seminars. Palgrave, London. https://doi.org/10.1007/978-1-349-03458-1_4
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DOI: https://doi.org/10.1007/978-1-349-03458-1_4
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