Thrombogenesis Caused by Blood-Foreign Surface Interaction

  • J. Feijen
Part of the Strathclyde Bioengineering Seminars book series (KESE)


Although the use of artificial organs in medicine has become well accepted, the blood compatibility of these devices needs further improvement. A survey of the blood damage caused by extracorporeal circuits is presented, followed by a discussion on mechanisms of blood-foreign material interactions. Attention is given to recent developments in the area of protein adsorption, platelet adhesion and activation of the intrinsic coagulation with special attention to the influence of flow conditions. Finally, some conclusions and future perspectives are outlined.


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© Bioengineering Unit, University of Strathclyde 1977

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  • J. Feijen

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