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Pathways of steroid metabolism in vivo studied by deuterium labeling techniques

  • T. A. Baillie
  • R. A. Anderson
  • M. Axelson
  • K. Sjövall
  • J. Sjövall

Abstract

Studies on the biosynthesis of progesterone in human pregnancy have indicated that the placenta has a very high capacity for the production of this steroid, and that rates of synthesis of up to 300 mg/day may be attained towards term (Solomon and Fuchs, 1971). However, it is not known why such large amounts of progesterone are required and what role, if any, its metabolites play in regulating hormonal activity.

Keywords

Deuterium Atom Steroid Metabolism Semilog Plot Deuterium Excess Steroid Sulphate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© The Contributors 1978

Authors and Affiliations

  • T. A. Baillie
    • 1
  • R. A. Anderson
    • 1
  • M. Axelson
    • 1
  • K. Sjövall
    • 1
  • J. Sjövall
    • 1
  1. 1.Department of Chemistry, Karolinska Institute and Department of Obstetrics and GynaecologyKarolinska HospitalStockholmSweden

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