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Abstract

In 1824 Prout934 demonstrated hydrochloric acid in human gastric juice and measured the concentration of acid by ‘exact neutralisation’ with strong alkali (indicator not stated: ? litmus). He also established the equation which we would write now as

[Total chloride] = [Neutral chloride] + [Titratable acid]

Prout expressed his concentrations as ‘grains in one pint’. In 1886 Jaworski and Gluzinski611 used 0.1 M NaOH and litmus and expressed concentrations as cc N/10 NaOH per 100 cc gastric juice or degrees of acidity, afterwards termed clinical units (numerically identical with mEq/l, mN and the SI unit mmol/l).

Keywords

Gastric Juice Parietal Cell Titratable Acidity Gastric Secretion Gastric Analysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© J. H. Baron 1978

Authors and Affiliations

  • J. H. Baron
    • 1
    • 2
  1. 1.Departments of Surgery and MedicineRoyal Postgraduate Medical School and Hammersmith HospitalUK
  2. 2.St Charles’ HospitalSt Mary’s Hospital Medical SchoolLondonUK

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