Regulation of gastric secretion

  • J. H. Baron


In the body of the stomach the parietal cells secrete acid and intrinsic factor, and the zymogen chief cells secrete pepsinogen which is converted by acid into pepsin. The surface epithelial and mucous neck cells of the body, and the pyloric cells of the antrum, secrete an alkaline mucus. Acid and intrinsic factor are secreted by the same cell, and the number of chief cells is correlated with the number of parietal cells, so that with few exceptions the measurement of acid alone gives a good indication of the gastric secretory capacity.


Acid Secretion Parietal Cell Gastric Secretion Intrinsic Factor Chief Cell 
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Copyright information

© J. H. Baron 1978

Authors and Affiliations

  • J. H. Baron
    • 1
    • 2
  1. 1.Departments of Surgery and MedicineRoyal Postgraduate Medical School and Hammersmith HospitalUK
  2. 2.St Charles’ HospitalSt Mary’s Hospital Medical SchoolLondonUK

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