Some aspects of renal physiology in the Brush-tailed possum, Trichosurus vulpecula
In the vertebrates the kidneys play a vital role in the regulation of the volume and composition of the extracellular fluid. To control this function a variety of mechanisms, both neural and endocrine, have evolved. These mechanisms have been studied extensively in eutherians but few detailed comparative investigations have been made. This is particularly true in the case of the marsupials. Until quite recently, little information was available on kidney structure and function and, in general, the data concerning the role of the adrenal cortex and the renin — angiotensin system in the regulation of fluid and electrolyte balance was very limited. It therefore seemed desirable to study renal physiology in the marsupials and to investigate in detail some of the mechanisms responsible for the regulation of renal function.
Unable to display preview. Download preview PDF.
- Blair-West, J. Coghlan, J. P., Denton, D. A., Nelson, J. F., Orchard, E., Scoggins, B.A., Wright, R. D., Myers, K. and Junqueira, C. L. (1968). Physiological, morphological and behavioural adaptation to a sodium deficient diet by wild native Australian and introduced species of animals. Nature, 217, 922–8.CrossRefPubMedGoogle Scholar
- Britton, S. W. (1931). Observations on adrenalectomy in marsupial, hibernating and higher mammalian types. Am. J. Physiol., 99, 9–14.Google Scholar
- Britton, S. W. and Sylvette, H. (1937). Further observations on sodium chloride balance in the adrenalectomised opossum. Am. J. Physiol., 118, 21–5.Google Scholar
- Chester Jones, I. (1957). The Adrenal Cortex, Cambridge University Press, London.Google Scholar
- Hollemans, H. J. G., Van der Meer, J. and Kloosterziel, W. (1969). Identification of the incubation product of Boucher’s renin activity assay, by means of radio-immunoassays for angiotensin I and angiotensin II, and a converting enzyme preparation from lung tissue. Clinica Chim. Acta, 23, 7–15.CrossRefGoogle Scholar
- Reid, I. A. (1973). Physiological mechanisms involved in the control of renin secretion. In: Excerpta Medica International Congress Series 302, pp. 300–11.Google Scholar
- Reid, I. A. and Ganong, W. F. (1974). The hormonal control of sodium excretion. In: Endocrine Physiology (ed. S. M. McCann ), MTP and Butterworths, London, pp. 205–37.Google Scholar
- Schmidt-Nielsen, K. and Newsome, A. E. (1962). Water balance in the mulgara (Dasycercus cristicauda), a carnivorous desert marsupial. Aust. J. Biol. Sci., 15, 683–9.Google Scholar
- Smith, H. W. (1951). The Kidney, Oxford University Press, New York. Sperber, I. (1944). Studies on the mammalian kidney. Zool. Bidr. Upps., 22, 249–432.Google Scholar
- Sylvette, H. and Britton, S. W. (1936). Carbohydrate and electrolyte changes in the opossum and marmot following adrenalectomy. Am. J. Physiol., 115, 618–26.Google Scholar
- Tubash, G. D. and Peart, W. S. (1966). Purification of human renin. Biochem. Biophys. Acta, 122, 289–97.Google Scholar
- Wilde, W. S. and Malvin, R. L. (1958). Graphical placement of transport segments along the nephron from urine concentration patterns developed with stop flow technique. Am. J. Physiol., 195, 153–60.Google Scholar