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The effects of some centrally acting drugs on the hexose transfer system in human erythrocytes

  • G. F. Baker
  • H. J. Rogers
Chapter
Part of the Biological Council book series

Abstract

It has recently become apparent that many centrally acting drugs exert at least part of their effect by interaction with the cell membrane (Seeman, 1972). The term ‘membrane stabilization’ was originally associated with the stabilization of resting potential against electrical stimulation (Guttman, 1940) but it now encompasses the action of drugs which at low concentrations protect the cell against osmotic, chemical or mechanical shock, while high concentrations are directly lytic to the cell membrane.

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Copyright information

© Institute of Biology Endowment Trust Fund 1973

Authors and Affiliations

  • G. F. Baker
    • 1
  • H. J. Rogers
    • 2
  1. 1.Department of Physiology, Bedford CollegeUniversity of LondonLondonEngland
  2. 2.Department of MedicineGuy’s Hospital Medical SchoolLondonEngland

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