The effects of some centrally acting drugs on the hexose transfer system in human erythrocytes
It has recently become apparent that many centrally acting drugs exert at least part of their effect by interaction with the cell membrane (Seeman, 1972). The term ‘membrane stabilization’ was originally associated with the stabilization of resting potential against electrical stimulation (Guttman, 1940) but it now encompasses the action of drugs which at low concentrations protect the cell against osmotic, chemical or mechanical shock, while high concentrations are directly lytic to the cell membrane.
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