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Pharmacological significance of new concepts for hexose transfers in erythrocytes

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Part of the book series: Biological Council

Abstract

Hexose transfers across red cell membranes involve a reaction between the sugar and some component or components of the cell membrane. The earliest kinetic data were readily explained by the mobile carrier model but the use of isotopes to measure sugar fluxes and the use of new experimental techniques to determine the kinetic parameters expected of the simple carrier model have produced inconsistencies and anomalies. These have accumulated until, in its simplest form, the mobile carrier model is no longer an adequate description of the process of facilitated transfer.

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© 1973 Institute of Biology Endowment Trust Fund

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Widdas, W.F. (1973). Pharmacological significance of new concepts for hexose transfers in erythrocytes. In: Callingham, B.A. (eds) Drugs and Transport Processes. Biological Council. Palgrave, London. https://doi.org/10.1007/978-1-349-02273-1_21

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