Summary
Biological cells exist in a saline environment which differs in ionic composition from the intracellular solution. Potassium is more concentrated inside, whereas sodium is more concentrated outside, cells. In the resting state, cell membranes are much more permeable to potassium than to sodium ions and this results in an electrical potential across the membrane, negative inside. The transmission of electrical signals, communication between cells, and the conversion of environmental energy to electrical signals, all depend on an inflow of sodium ions into cells as a result of an increase in the sodium permeability of the cell membrane. The intracellular concentrations of sodium and potassium ions are regulated by metabolically ‘fuelled’ ionic pumps. Because membrane potentials are essentially ionic diffusion potentials, the concentration gradients of sodium and potassium ions are of fundamental importance in the generation of electrical signals which are hence very sensitive to the concentration of these ions in the extracellular saline.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Goldman, D. E. (1943). J. gen. Physiol. 27, 37.
Hodgkin, A. L. (1937). J. Physiol. (Lond.) 90, 183.
Hodgkin, A. L. (1964). The Conduction of the Nervous Impulse. Liverpool University Press, Liverpool.
Hodgkin, A. L., and Horowicz, P. (1959a). J. Physiol. (Lond.) 145, 405.
Hodgkin, A. L., and Horowicz, P. (1959b). J. Physiol. (Lond.) 148, 127.
Hodgkin, A. L., and Katz, B. (1949). J. Physiol. (Lond.) 108, 37.
Hodgkin, A. L., and Keynes, R. D. (1955). J. Physiol. (Lond.) 128, 28.
Katz, B. (1966). Nerve, Muscle and Synapse. McGraw-Hill, New York.
Miledi, R. and Slater, C. R. (1966). J. Physiol. (Lond.) 184, 473.
Nastuk, W. L. and Hodgkin, A. L. (1950). J. Cell. Comp. Physiol. 35, 39.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Copyright information
© 1971 Australian Academy of Science
About this chapter
Cite this chapter
Gage, P.W. (1971). Salinity and Animal Cells. In: Talsma, T., Philip, J.R. (eds) Salinity and Water Use. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-01391-3_11
Download citation
DOI: https://doi.org/10.1007/978-1-349-01391-3_11
Publisher Name: Palgrave Macmillan, London
Print ISBN: 978-1-349-01393-7
Online ISBN: 978-1-349-01391-3
eBook Packages: Earth and Environmental ScienceEarth and Environmental Science (R0)