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The Effects of Steroid Hormones and Carcinogens on the Interaction of Membranes with Polysomes

  • Chapter
Effects of Drugs on Cellular Control Mechanisms

Part of the book series: Biological Council ((BCSDA))

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Abstract

Protein synthesis in the cell, involves particulate elements called ribosomes which translate the information coded as specific nucleotide sequences in messenger RNA molecules into amino-acid sequences of proteins [1]. Ribosomes are frequently found in the cell in the form of aggregates called polysomes. The ribosomes in a polysome are believed to be attached to a single messenger RNA molecule and simultaneously to translate the encoded information to give polypeptides with a specific amino-acid sequence [2]. The basic mechanisms of the control of protein synthesis at the level of translation are not well understood.

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Author information

Authors and Affiliations

  1. Department of Biochemistry, University College London, Gower Street, London, WC1E 6BT, UK

    B. R. Rabin, Carol A. Blyth, Delma Doherty, R. B. Freedman, Anne Roobol, G. Sunshine & D. J. Williams

Authors
  1. B. R. Rabin
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  2. Carol A. Blyth
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  3. Delma Doherty
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  4. R. B. Freedman
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  5. Anne Roobol
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  6. G. Sunshine
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  7. D. J. Williams
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Editor information

Editors and Affiliations

  1. Department of Biochemistry, University College, London, UK

    B. R. Rabin

  2. Biology Laboratory, University of Kent, Canterbury, UK

    R. B. Freedman

Copyright information

© 1971 Institute of Biology Endowment Fund

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Rabin, B.R. et al. (1971). The Effects of Steroid Hormones and Carcinogens on the Interaction of Membranes with Polysomes. In: Rabin, B.R., Freedman, R.B. (eds) Effects of Drugs on Cellular Control Mechanisms. Biological Council. Palgrave, London. https://doi.org/10.1007/978-1-349-01321-0_3

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