Dietary Aflatoxin Loads and the Incidence of Human Hepatocellular Carcinoma in Thailand

  • R. C. Shank


In mid-1967, a research project was initiated to investigate the possible role mycotoxins may play in the aetiology of human liver disease in southeast Asia. This present report is concerned with the results of 3 years of study in Thailand. Thailand was chosen as the principal country of the study because climate and agricultural practices favour mycotoxin contamination of foods and foodstuffs and because several reports indicated that certain areas of south-east Asia, Thailand in particular, suffer from apparent high incidences of liver disease, especially hepatocellular carcinoma.1–4


Liver Cancer Primary Liver Cancer Total Daily Dose Aflatoxin Contamination Human Liver Cancer 
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  1. 1.
    Berman, C. (1951). In: Primary Carcinoma of the Liver. H. K. Lewis and Co., London.Google Scholar
  2. 2.
    Takeda, J. and Aizawa, M. (1956). Trans. Soc. Path. Japan, 45, 1Google Scholar
  3. 3.
    Bhamarapravati, N. and Nimsomburna, P. (1963). Proc. 16th Assembly Japan Med. Cong., 3, 376.Google Scholar
  4. 4.
    Bhamarapravati, N. and Viranuvatti, V. (1966). Am. J. Gastroent., 45, 267.PubMedGoogle Scholar
  5. 5.
    Shank, R. C., Gibson, J. B., Chong, Y. H. and Wogan, G. N. In preparation.Google Scholar
  6. 6.
    Shank, R. C., Gibson, J. B., Chong, Y. H., Nondasut, A. and Wogan, G. N. In preparation.Google Scholar
  7. 7.
    Eppley, R. M. (1966). J. Assoc. Offic. Anal. Chemists, 49, 1218.Google Scholar
  8. 8.
    Wogan, G. N. and Newberne, P. M. (1967). Cancer Res., 27, 2370.PubMedGoogle Scholar

Copyright information

© South African Medical Research Council 1971

Authors and Affiliations

  • R. C. Shank
    • 1
  1. 1.Department of Nutrition and Food ScienceMassachusetts Institute of TechnologyCambridgeUSA

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