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The Acute and Chronic Toxicity of Sterigmatocystin

  • I. F. H. Purchase
  • J. J. van der Watt

Abstract

The widespread occurrence of toxigenic fungi in foods and the potent carcinogenic action of aflatoxin to various laboratory animals have caused much speculation on the possible relationships between mycotoxin ingestion and the high incidence of malignant hepatoma in man in Africa. The possibility that mycotoxins other than aflatoxin may be responsible has been stressed and sterigmatocystin, a metabolite of the moulds Aspergillus nidulans, Aspergillus versicolor and a Bipolaris sp., chemically related to aflatoxin, was therefore studied.

Keywords

Fatty Change Vervet Monkey Hyperplastic Nodule Aspergillus Versicolor Toxigenic Fungus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Purchase, I. F. H. and Van Der Watt, J. J. (1968). Fd. Cosmet. Toxicol., 6, 555–556.CrossRefGoogle Scholar
  2. 2.
    Purchase, I. F. H. and Van Der Watt, J. J. (1969). Fd. Cosmet. Toxicol., 7, 135–139.CrossRefGoogle Scholar
  3. 3.
    Van Der Watt, J. J. and Purchase, I. F. H. (1970). S.A. med. J., 44, 159–160.Google Scholar
  4. 4.
    Van Der Watt, J. J. and Purchase, I. F. H. (1970). Br. J. exp. Path., 51, 183–190.Google Scholar
  5. 5.
    Torres, F. O., Purchase, I. F. H. and Van Der Watt, J. J. (1970). J. Path., 102, 163–169.CrossRefPubMedGoogle Scholar

Copyright information

© South African Medical Research Council 1971

Authors and Affiliations

  • I. F. H. Purchase
    • 1
  • J. J. van der Watt
    • 1
  1. 1.Division of ToxicologyNational Institute for Nutritional Diseases South African Medical Research CouncilSouth Africa

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