The Metabolism and Some Metabolic Effects of Sterigmatocystin

  • W. Nel
  • P. G. Kempff
  • M. J. Pitout


The influence of the metabolites of carcinogens and toxins on macromolecules is becoming of increasing interest in the study of the biochemistry of tumours. Sterigmatocystin, with a chemical structure closely related to aflatoxin, is carcinogenic to rats1 and there are indications that it may also be carcinogenic to Vervet monkeys.2 The type of tumour produced experimentally with sterigmatocystin is morphologically similar to tumours seen in the Bantu races of Southern Africa.


Sodium Lauryl Sulphate Aspergillus Nidulans Zinc Sulphate Vervet Monkey Anhydrous Calcium Chloride 
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Copyright information

© South African Medical Research Council 1971

Authors and Affiliations

  • W. Nel
    • 1
  • P. G. Kempff
    • 2
  • M. J. Pitout
    • 2
  1. 1.University College of ZululandSouth Africa
  2. 2.Division of ToxicologyNational Institute for Nutritional Diseases South African Medical Research CouncilSouth Africa

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