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Calcium and the Action Potential in Smooth Muscle

  • Edith Bülbring
  • T. Tomita
Part of the Biological Council book series

Abstract

In most excitable membranes the action potential is produced by an inward movement of Na ions across the membrane. The maximum rate of rise in nerve is about 500 V/sec and is roughly proportional to the external Na concentration (Hodgkin & Katz, 1949). The action potential is abolished in Na-free solution. It is also known, however, that in some crustacean muscle fibres, Ca ions, not Na ions, carry the inward current for the production of the action potential (Hagiwara & Naka, 1964). The removal of Na ions from the external solution does not, therefore, change the size or the shape of the action potential.

Keywords

Spike Activity External Solution Membrane Resistance Locke Solution Constant Current Pulse 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Palgrave Macmillan, a division of Macmillan Publishers Limited 1970

Authors and Affiliations

  • Edith Bülbring
    • 1
  • T. Tomita
    • 2
  1. 1.Department of PharmacologyUniversity of OxfordUSA
  2. 2.Department of PhysiologyKyushu UniversityJapan

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