Site of Protein Secretion and Calcium Accumulation in the Polymorphonuclear Leucocyte Treated with Leucocidin
The two proteins that constitute leucocidin induce changes in the polymorphonuclear leucocytes of rabbit and man that mimic those in excitable or secreting tissues during membrane depolarization or stimulation by hormones (Woodin, 1968). This was known to be true in a descriptive sense several years ago (Woodin & Wieneke, 1966a), and recent work suggests that it is also true of the mechanisms. Thus diisopropyl phosphorofluoridate (DFP) and tetraethylammonium ions modify the effects of leucocidin and the axon in similar conditions (Woodin & Wieneke, 1968a, 1969).
KeywordsProtein Secretion Calcium Accumulation Granule Protein Cell Surface Membrane Isolate Cell Membrane
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