Advertisement

Calcium and Hormone Release

  • E. K. Matthews
Part of the Biological Council book series

Abstract

The calcium ion plays an essential part in the liberation of transmitter at chemically operated synapses. Yet its involvement in the more general process of hormone release may be no less critical. Thus the synaptic release of acetylcholine and noradrenaline is calcium dependent (Harvey & MacIntosh, 1940; del Castillo & Stark, 1952; Huković & Muscholl, 1962; Kirpekar & Misu, 1967); but so, too, is the release of many hormones (Table 1). Furthermore, stimulation of the neurohypophysis and adrenal medulla causes a five- to eight-fold increase in the rate of 45Ca2+ uptake by these tissues (Douglas & Poisner, 1962, 1964).

Keywords

Luteinizing Hormone Islet Cell Adrenal Medulla Hormone Release Granule Membrane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Banks, P. (1966). Biochem. J., 101, 18cCrossRefGoogle Scholar
  2. Bianchi, C. P. & Shanes, A. M. (1959). J. gen. Physiol., 42, 803PubMedCentralCrossRefPubMedGoogle Scholar
  3. Bindler, E., Labella, F. S. & Sanwal, M. (1967). J. cell Biol., 34, 185PubMedCentralCrossRefPubMedGoogle Scholar
  4. Blioch, Z. L., Glagoleva, I. M., Liberman, E. A. & Nenashev, V. A. (1968). J. Physiol., Lond., 199, 11PubMedCentralCrossRefPubMedGoogle Scholar
  5. Del Castillo, J. & Stark, L. (1952). J. Physiol., Lond., 116, 507PubMedCentralCrossRefGoogle Scholar
  6. Chambers, R. & Kao, C. Y. (1952). Exp. cell Res., 3, 564CrossRefGoogle Scholar
  7. Coupland, R. E. (1965). In The Natural History of the Chromaffin Cell. London: Longmans, GreenGoogle Scholar
  8. Curtis, A. S. G. (1967). In The Cell Surface: its Molecular Role in Morphogenesis. London: Logos Press; Academic PressGoogle Scholar
  9. Daniel, A. R. & Lederis, K. (1963). Gen. comp. Endocr., 3, 693Google Scholar
  10. Dean, P. M. & Matthews, E. K. (1968). Nature, Lond., 219, 389CrossRefGoogle Scholar
  11. Dean, P. M. & Matthews, E. K. (1969). J. Physiol., Lond., in the PressGoogle Scholar
  12. Dicker, S. E. (1966). J. Physiol., Lond., 185, 429PubMedCentralCrossRefPubMedGoogle Scholar
  13. Douglas, W. W. (1968). Br. J. Pharmac., 34, 451CrossRefGoogle Scholar
  14. Douglas, W. W. & Poisner, A. M. (1962). J. Physiol., Lond., 162, 385PubMedCentralCrossRefPubMedGoogle Scholar
  15. Douglas, W. W. & Poisner, A. M. (1964). J. Physiol., Lond., 172, 19PubMedCentralCrossRefPubMedGoogle Scholar
  16. Douglas, W. W. & Poisner, A. M. (1966). J. Physiol., Lond., 183, 236PubMedCentralCrossRefPubMedGoogle Scholar
  17. Douglas, W. W. & Rubin, R. P. (1961). J. Physiol., Lond., 159, 40PubMedCentralCrossRefPubMedGoogle Scholar
  18. Ginsburg, M. & Ireland, M. (1966). J. Endocrinol., 35, 289CrossRefPubMedGoogle Scholar
  19. Grodsky, G. M. & Bennett, L. L. (1966). Diabetes, 15, 910CrossRefPubMedGoogle Scholar
  20. Hagiwara, S. & Nakajima, S. (1966). J. gen. Physiol., 49, 793PubMedCentralCrossRefPubMedGoogle Scholar
  21. Hales, C. N. & Milner, R. D. G. (1968). J. Physiol., Lond., 199, 177PubMedCentralCrossRefPubMedGoogle Scholar
  22. Harvey, A. M. & Macintosh, F. C. (1940). J. Physiol., Lond., 97, 408PubMedCentralCrossRefPubMedGoogle Scholar
  23. Heilbrunn, L. V. (1956). In The Dynamics of Living Protoplasm. New York: Academic PressGoogle Scholar
  24. Hodgkin, A. L. & Katz, B. (1949). J. exp. Biol., 26, 292PubMedGoogle Scholar
  25. Hodgkin, A. L. & Keynes, R. D. (1957). J. Physiol., Lond., 138, 253PubMedCentralCrossRefPubMedGoogle Scholar
  26. Kfelt, T. (1968). Z. Zellforsch., 91, 1.CrossRefPubMedGoogle Scholar
  27. Hubbard, J. I. & Kwanbunbumpen, S. (1968). J. Physiol., Lond., 194, 407PubMedCentralCrossRefPubMedGoogle Scholar
  28. HukoviÈ, S. & Muscxoll, E. (1962). Arch. exp. Path. Pharmak., 244, 81CrossRefGoogle Scholar
  29. Hymer, W. C. & Mcshan, W. H. (1963). J. cell Biol., 17, 67PubMedCentralCrossRefPubMedGoogle Scholar
  30. Ishida, A. (1968). Jap. J. Physiol., 18, 471.CrossRefGoogle Scholar
  31. Kirpekar, S. M. & Misu, Y. (1967). J. Physiol., Lond., 188, 219PubMedCentralCrossRefPubMedGoogle Scholar
  32. Kirschner, N., Sage, H. J. & Smith, W. J. (1967). Mol. Pharmac., 3, 254Google Scholar
  33. Lacy, P. E., Howell, S. L., Young, D. A. & Fink, C. J. (1968). Nature, Lond., 219, 1177CrossRefGoogle Scholar
  34. Lazarus, S. S., Shapiro, S. N. & Volk, B. W. (1967). Lab. Invest., 16, 330PubMedGoogle Scholar
  35. Malamed, S., Poisner, A. M., TrÎfarÓ, J. M. & Douglas, W. W. (1968). Biochem. Pharmac., 17, 241CrossRefGoogle Scholar
  36. Matthews, E. K. & Dean, P. M. (1969). In The Structure and Function of Pancreatic Islets, ed. Falkmer, S., Hellman, B. & TÄLjedal, I.-B. London: Pergamon, in the PressGoogle Scholar
  37. Meves, H. (1966). Ann. N.Y. Acad. Sci., 137, 807CrossRefPubMedGoogle Scholar
  38. Meyer, J. & Bencosme, S. A. (1965). Rev, can. Biol., 24, 179Google Scholar
  39. Milner, R. D. G. & Hales, C. N. (1967). Diabetologia, 3, 47CrossRefPubMedGoogle Scholar
  40. Overbeek, J. Th. G. (1952). In Colloid Science I, ed. Kruyt, H. M. Amsterdam: ElsevierGoogle Scholar
  41. Pethica, B. A. (1961). Exp. cell Res. Suppl., 8, 123CrossRefGoogle Scholar
  42. Perdue, J. F. & Mcshan, W. H. (1966). Endocrinology, 78, 406CrossRefPubMedGoogle Scholar
  43. Poisner, A. M. & Douglas, W. W. (1968). Mol. Pharmac., 4, 531Google Scholar
  44. Poisner, A. M. & TrifarÔ, J. M. (1967). Mol. Pharmac., 3, 561Google Scholar
  45. Porter, K. R. (1966). In Principles of Biomolecular Organization, ed. Wolstenholme, G. E. W. & O’Connor, M., p. 308. London: ChurchillGoogle Scholar
  46. Rieser, P. (1949). Biol. Bull., 97, 245Google Scholar
  47. Rubin, R. P., Feinstein, M. B., Jaanus, S. D. & Paimre, M. (1967). J. Pharmac. exp. Ther., 155, 463Google Scholar
  48. Sachs, H. (1967). Am. J. Med., 42, 687CrossRefPubMedGoogle Scholar
  49. Sachs, H. & Haller, E. W. (1968). Endocrinology, 83, 251CrossRefPubMedGoogle Scholar
  50. Samli, M. H. & Geschwind, I. I. (1968). Endocrinology, 82, 225CrossRefPubMedGoogle Scholar
  51. Schneider, F. H., Smith, A. D. & Winkler, H. (1967). Br. J. Pharmac. Chemother., 31, 94CrossRefGoogle Scholar
  52. Shea, S. M. & Karnovsky, M. J. (1966). Nature, Lond., 212, 253CrossRefGoogle Scholar
  53. Siperstein, E. R. (1963). J. cell Biol., 17, 521PubMedCentralCrossRefPubMedGoogle Scholar
  54. Siperstein, E. R. & Allison, V. F. (1965). Endocrinology, 76, 70CrossRefPubMedGoogle Scholar
  55. Thorn, N. A. (1965). Acta endocr., Copenh., 50, 357Google Scholar
  56. Vale, W., Burgus, R. & Guillemin, R. (1967). Experientia, 13, 853CrossRefGoogle Scholar
  57. Vale, W. & Guillemin, R. (1967). Experientia, 13, 855CrossRefGoogle Scholar
  58. Vervey, E. J. W. & Overbeek, J. Th. G. (1948). Theory of the Stability of Lyophobic Colloids. Amsterdam: ElsevierGoogle Scholar
  59. Whittaker, V. P. (1965). Progr. Biophys. Mol. Biol., 15. 39CrossRefGoogle Scholar
  60. Whittaker, V. P. (1968). Br. med. Bull., 24, 101PubMedGoogle Scholar

Copyright information

© Palgrave Macmillan, a division of Macmillan Publishers Limited 1970

Authors and Affiliations

  • E. K. Matthews
    • 1
  1. 1.Department of PharmacologyUniversity of CambridgeUK

Personalised recommendations