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Raising the Technological Level: The Scope for API, Excipients, and Biologicals Manufacture in Africa

  • Joseph Fortunak
  • Skhumbuzo Ngozwana
  • Tsige Gebre-Mariam
  • Tiffany Ellison
  • Paul Watts
  • Martins Emeje
  • Frederick E. NytkoIII
Part of the International Political Economy Series book series (IPES)

Abstract

This chapter discusses raising the technological scope for locally manufacturing active pharmaceutical ingredients (APIs), excipients and biologicals in Africa — a hitherto nascent industry. It also discusses African drug development and manufacturing through the standardized use of ‘reverse pharmacology’ to bring new treatments for neglected diseases to the point of regulatory approvals. Currently there is very modest production of APIs on the African continent, although a few significant projects exist,1 (such as LaGray in Ghana and Fine Chemicals in South Africa), or are in the planning stages.2 Generic producers in India and China supply nearly all of the APIs used in African pharmaceutical manufacturing. Most African companies cannot afford the heavy investment and research and development activities required for API production.

Keywords

Tenofovir Disoproxil Fumarate Good Manufacturing Practice Technological Level Quality Management System Pharmaceutical Manufacturing 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Joseph Fortunak, Skhumbuzo Ngozwana, Tsige Gebre-Mariam, Tiffany Ellison, Paul Watts, Martins Emeje and Frederick E. Nytko III 2016

Open Access This Chapter is distributed under the terms of the Creative Commons Attribution Noncommercial License, which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

Authors and Affiliations

  • Joseph Fortunak
  • Skhumbuzo Ngozwana
  • Tsige Gebre-Mariam
  • Tiffany Ellison
  • Paul Watts
  • Martins Emeje
  • Frederick E. NytkoIII

There are no affiliations available

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