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Chemotherapy in Inflammatory Breast Cancer

  • Claudia Arce-Salinas
  • Flavia Morales-Vasquez
  • Fernando Lara-Medina
  • Silvia Patricia Villarreal-Colin
Chapter

Abstract

Inflammatory breast cancer has poor prognosis. Without systemic therapy, the 5-year survival was 4 %. Since 1970s, with the introduction of neoadjuvant chemotherapy in the treatment of this tumor, the prognosis has changed. The first attempt of systemic therapy was done with 5-FU given for long time but with improvement in DFS. Later, the incorporation of chemoimmunotherapy based on BCG, however, due to the lack of specificity and the same results without BCG, this modality was abandoned. Finally, regimens based on anthracyclines and taxanes have become the standard of care, not to mention the importance of multimodal treatment.

Keywords

Overall Survival Autologous Stem Cell Transplantation Inflammatory Breast Cancer Locally Advanced Breast Cancer Optimal Local Control 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag London 2013

Authors and Affiliations

  • Claudia Arce-Salinas
    • 1
  • Flavia Morales-Vasquez
    • 1
  • Fernando Lara-Medina
    • 1
  • Silvia Patricia Villarreal-Colin
    • 1
  1. 1.Department of Medical OncologyInstituto Nacional de Cancerologia-MexicoTlalpan, Mexico CityMexico

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