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Gram-Negative Bacteria Possess Sequences Which Resemble the ‘Shared Epitope’ but Only Proteus Infect Rheumatoid Arthritis Patients

  • Alan Ebringer
Chapter

Abstract

The ‘shared epitope’ EQRRAA has been found to resemble or show ‘molecular mimicry’ with the sequence ESRRAL spanning residues 32–37 of the surface membrane haemolysin of Proteus mirabilis (Hpm B polypeptide).

The same hexamer sequence was also found in the membrane haemolysin of Serratia marcescens (Shl B polypeptide).

Keywords

Rheumatoid Arthritis Rheumatoid Arthritis Patient Pseudomonas Aeruginosa Healthy Control Subject Rheumatic Fever 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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Copyright information

© Springer-Verlag London Limited 2011

Authors and Affiliations

  • Alan Ebringer
    • 1
  1. 1.King’s College London Division of Life SciencesUCH School of MedicineLondonUK

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