Fatigue in Primary Sjögren’s Syndrome

  • Barbara M. Segal


Recognition of a syndrome characterized by fatigue in patients without an obvious cardiopulmonary illness dates back to the late nineteenth century [1–3]. Early descriptions of patients with “neurasthenia” focused on the substantial weakness and lassitude accompanying the syndrome, which was particularly prominent among women. Following the conclusion of the First World War, physicians were challenged by the large numbers of battle-scarred veterans afflicted by chronic fatigue [4].


Irritable Bowel Syndrome Sleep Quality Primary Biliary Cirrhosis Chronic Fatigue Syndrome Fatigue Severity Scale 
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Copyright information

© Springer-Verlag London Limited 2011

Authors and Affiliations

  • Barbara M. Segal
    • 1
    • 2
  1. 1.Division of Rheumatic and Autoimmune DisordersUniversity of Minnesota Medical SchoolMinneapolisUSA
  2. 2.Department of MedicineHennepin County Medical CenterMinneapolisUSA

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