Primary Sjögren Syndrome in Primary Health Care

  • Antoni Sisó-Almirall
  • Jaume Benavent
  • Xavier Bosch
  • Albert Bové
  • Manuel Ramos-Casals


Sjogren’s syndrome (SjS) is a slowly progressive autoimmune disease that predominantly affects middle-aged women, with a female to male ratio on the order of 9:1. SS is characterized by lymphocytic infiltration of the exocrine glands, mainly the lacrimal and salivary glands, resulting in reduced secretory function and oral and ocular dryness. The syndrome can present alone as primary SjS (pSjS) or in the context of underlying connective tissue disease as secondary SjS (sSjS). Although the pathogenesis of the disease remains elusive, environmental, genetic and hormonal factors all appear to contribute [1].


Rose Bengal Salivary Flow Rate Primary Care Practitioner Keratoconjunctivitis Sicca Sicca Symptom 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag London Limited 2011

Authors and Affiliations

  • Antoni Sisó-Almirall
    • 1
  • Jaume Benavent
    • 1
  • Xavier Bosch
    • 2
  • Albert Bové
    • 3
  • Manuel Ramos-Casals
    • 3
  1. 1.Research Group on Primary Care, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), CAP Les Corts, GesClínicUniversity of BarcelonaBarcelonaSpain
  2. 2.Department of Internal MedicineICMiD, Hospital ClínicBarcelonaSpain
  3. 3.Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Autoimmune DiseasesHospital ClínicBarcelonaSpain

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