Sjögren’s Syndrome and Associations with Other Autoimmune and Rheumatic Diseases

  • James E. Peters
  • David A. Isenberg


Sjögren’s syndrome (SS) is an autoimmune exocrinopathy that manifests itself most commonly as dryness of the mucosal surfaces. Systemic or extraglandular features can also occur. Both primary and secondary forms of SS are recognized to exist. In the latter, the syndrome develops in a patient with another systemic autoimmune disease such as rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE). The secondary form of SS is the focus of this chapter. The current nomenclature struggles to classify patients with mixed features of SS and another autoimmune condition. The term “Sjögren’s overlap” has been proposed to describe such patients.


Systemic Lupus Erythematosus Rheumatoid Arthritis Patient Systemic Lupus Erythematosus Patient Coeliac Disease Mixed Connective Tissue Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag London Limited 2011

Authors and Affiliations

  • James E. Peters
    • 1
  • David A. Isenberg
    • 1
  1. 1.Department of RheumatologyUniversity College London HospitalLondonUK

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