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Sjögren’s Syndrome pp 347–366Cite as

Laboratory Abnormalities in Primary Sjögren’s Syndrome

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Abstract

Sjögren’s syndrome (SS) is a systemic autoimmune disease that presents with sicca symptomatology of the main mucosa surfaces. The spectrum of the disease extends from sicca syndrome to systemic involvement (extraglandular manifestations) and may be complicated by the development of lymphoma. Patients with SS may present with a broad spectrum of autoantibodies and laboratory abnormalities. Most of the laboratory abnormalities have been described more frequently in patients with positive immunological markers. Some may be the first manifestation of primary SS, while others have no clinical significance.

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Authors and Affiliations

  1. Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Spain

    Pilar Brito-Zerón & Manuel Ramos-Casals

  2. Department of Internal Medicine, Hospital Meixoeiro, Vigo, Spain

    Roberto Pérez-Alvarez & Marta Pérez-de-Lis

  3. Department of Internal Medicine, Hospital Virgen de las Nieves, Granada, Spain

    Carmen Hidalgo-Tenorio

Authors
  1. Pilar Brito-Zerón
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  2. Roberto Pérez-Alvarez
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  3. Marta Pérez-de-Lis
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  4. Carmen Hidalgo-Tenorio
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  5. Manuel Ramos-Casals
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Editor information

Editors and Affiliations

  1. Barcelona, Surgey, Hospital Clinic, Calle Villarroel, 170, Barcelona, 08036, Spain

    Manuel Ramos-Casals

  2. Massachusetts General Hospital, Boston, 02114, Massachusetts, USA

    John H. Stone

  3. National University of Athens, Athens, Greece

    Haralampos M. Moutsopoulos

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© 2011 Springer-Verlag London Limited

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Brito-Zerón, P., Pérez-Alvarez, R., Pérez-de-Lis, M., Hidalgo-Tenorio, C., Ramos-Casals, M. (2011). Laboratory Abnormalities in Primary Sjögren’s Syndrome. In: Ramos-Casals, M., Stone, J., Moutsopoulos, H. (eds) Sjögren’s Syndrome. Springer, London. https://doi.org/10.1007/978-0-85729-947-5_25

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  • DOI: https://doi.org/10.1007/978-0-85729-947-5_25

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  • Publisher Name: Springer, London

  • Print ISBN: 978-0-85729-946-8

  • Online ISBN: 978-0-85729-947-5

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