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Laboratory Abnormalities in Primary Sjögren’s Syndrome

  • Pilar Brito-Zerón
  • Roberto Pérez-Alvarez
  • Marta Pérez-de-Lis
  • Carmen Hidalgo-Tenorio
  • Manuel Ramos-Casals
Chapter

Abstract

Sjögren’s syndrome (SS) is a systemic autoimmune disease that presents with sicca symptomatology of the main mucosa surfaces. The spectrum of the disease extends from sicca syndrome to systemic involvement (extraglandular manifestations) and may be complicated by the development of lymphoma. Patients with SS may present with a broad spectrum of autoantibodies and laboratory abnormalities. Most of the laboratory abnormalities have been described more frequently in patients with positive immunological markers. Some may be the first manifestation of primary SS, while others have no clinical significance.

Keywords

Aplastic Anemia Pernicious Anemia Chronic Atrophic Gastritis Monoclonal Immunoglobulin Sicca Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag London Limited 2011

Authors and Affiliations

  • Pilar Brito-Zerón
    • 1
  • Roberto Pérez-Alvarez
    • 2
  • Marta Pérez-de-Lis
    • 2
  • Carmen Hidalgo-Tenorio
    • 3
  • Manuel Ramos-Casals
    • 1
  1. 1.Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Autoimmune DiseasesHospital ClínicBarcelonaSpain
  2. 2.Department of Internal MedicineHospital MeixoeiroVigoSpain
  3. 3.Department of Internal MedicineHospital Virgen de las NievesGranadaSpain

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