Acute Liver Injury and Failure in Children

  • Richard L. Lambert


Acute liver failure (ALF) in children is uncommon. It can occur at any age and have a variety of presentations. A major challenge is to quickly determine the etiology and initiate appropriate therapy. Even with rapid diagnosis and aggressive medical management, patients may progress to irreversible liver failure and require transplantation. A multidisciplinary approach including early consultation with a transplant specialist can improve outcome. This chapter reviews the current understanding of ALF in children with specific attention to etiology, evaluation and diagnosis, and treatment options.


Hepatic Encephalopathy Pediatric Intensive Care Unit Disseminate Intravascular Coagulation Continuous Renal Replacement Therapy Acute Liver Failure 
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Copyright information

© Springer-Verlag London Limited 2012

Authors and Affiliations

  1. 1.Pediatric Critical Care Medicine, Department of Pediatrics, Geisinger Medical CenterTemple University School of Medicine, Janet Weis Children’s HospitalDanvilleUSA

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