Lymphadenectomy in Endometrial Cancer: The Controversy Rages Unabated

  • Henry C. Kitchener
  • Kristina A. Butler
  • Emma J. Crosbie
  • Andrea Mariani


The role of lymphadenectomy in endometrial cancer continues to provoke debate. The Mayo School advocates its use for the appropriate classification and treatment of those at risk of recurrent disease. The Manchester School argues that its use cannot be justified without clear evidence for a survival benefit. In this chapter, both sides of the debate are presented alongside a mutually agreeable trial design that has the potential to provide conclusive evidence, once and for all, for how early-stage endometrial cancer should be managed.


Sentinel Node Adjuvant Therapy Endometrial Cancer Myometrial Invasion Systematic Lymphadenectomy 
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Copyright information

© Springer-Verlag London 2014

Authors and Affiliations

  • Henry C. Kitchener
    • 1
  • Kristina A. Butler
    • 2
  • Emma J. Crosbie
    • 3
  • Andrea Mariani
    • 2
  1. 1.Department of Obstetrics and GynaecologyInstitute of Cancer Sciences, St. Mary’s Hospital, University of ManchesterManchesterUK
  2. 2.Obstetrics and GynecologyMayo ClinicRochesterUSA
  3. 3.Academic Unit of Obstetrics and GynaecologyInstitute of Cancer Sciences, St. Mary’s Hospital, University of ManchesterManchesterUK

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