What Is the Role of PET/CT in Gynecological Cancers?

  • Joanne Alfieri
  • Kailash Narayan
  • Andrea Rockall


Molecular imaging, in particular, integrated positron emission tomography/computed tomography with the glucose analogue 2-[18F] fluoro-2-deoxy-D-glucose (18F-FDG-PET/CT), has added another dimension to oncology practice. Over the past decade, this modality has influenced diagnosis, staging, patient management, treatment planning, and posttreatment surveillance in a variety of tumor sites, including gynecological malignancies. However, its application is not without limitations and controversies. This chapter discusses these controversies with respect to cervical, endometrial, and ovarian cancers. In particular, whether this modality has any usefulness in the staging of cervical cancer, in the surgical decision-making prior to hysterectomy in endometrial cancer, or in its application as a treatment response tool in ovarian cancer. The use of 18F-FDG-PET/CT in the management of gynecological malignancies is still evolving and further studies are required to optimize its role in these diseases.


Positron Emission Tomography Ovarian Cancer Cervical Cancer Endometrial Cancer Standardize Uptake Value 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag London 2014

Authors and Affiliations

  • Joanne Alfieri
    • 1
  • Kailash Narayan
    • 2
  • Andrea Rockall
    • 3
  1. 1.Department of Radiation OncologyMcGill University Health Centre, Montreal General HospitalMontrealCanada
  2. 2.Department of Radiation OncologyPeter MacCallum Cancer CentreEast MelbourneAustralia
  3. 3.Department of RadiologyImperial College Healthcare NHS Trust, Hammersmith HospitalLondonUK

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