Percutaneous Bone Marrow Aspirate Harvesting from the Anterior Iliac Crest

  • Rozalia I. Dimitriou
  • Nikolaos K. Kanakaris
  • Peter V. Giannoudis


Bone marrow aspirate from the iliac crest contains mesenchymal stem cells (MSCs) and growth factors that can be used to stimulate bone regeneration. The marrow has been estimated to contain 1/50,000 nucleated stem cells in younger adults and 1/1,000,000 in the elderly. Both anterior and posterior iliac crests can be used for bone marrow aspiration. In this chapter, we will describe the aspiration technique from the anterior iliac crest.


Iliac Crest Anterior Superior Iliac Spine Iliac Crest Bone Grafting Lateral Femoral Cutaneous Nerve Posterior Iliac Crest 
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Further Readings

  1.  .
    Cho HS, Oh JH, Kim HS, Kang HG, Lee SH. Unicameral bone cysts: a comparison of injection of steroid and grafting with autologous bone marrow. J Bone Joint Surg Br. 2007;89(2):222–6.PubMedCrossRefGoogle Scholar
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    Gangji V, Hauzeur JP, Matos C, De Maertelaer V, Toungouz M, Lambermont M. Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells. A pilot study. J Bone Joint Surg Am. 2004;86-A(6):1153–60.PubMedGoogle Scholar
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    Hernigou P, Mathieu G, Poignard A, Manicom O, Beaujean F, Rouard H. Percutaneous autologous bone-marrow grafting for nonunions. Surgical technique. J Bone Joint Surg Am. 2006;88(Suppl 1 Pt 2):322–7.PubMedCrossRefGoogle Scholar
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    Hernigou P, Poignard A, Beaujean F, Rouard H. Percutaneous autologous bone-marrow grafting for nonunions. Influence of the number and concentration of progenitor cells. J Bone Joint Surg Am. 2005;87(7):1430–7.PubMedCrossRefGoogle Scholar
  5.  .
    Hernigou P, Poignard A, Manicom O, Mathieu G, Rouard H. The use of percutaneous autologous bone marrow transplantation in nonunion and avascular necrosis of bone. J Bone Joint Surg Br. 2005;87(7):896–902.PubMedCrossRefGoogle Scholar
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    Muschler GF, Nitto H, Matsukura Y, Boehm C, Valdevit A, Kambic H, et al. Spine fusion using cell matrix composites enriched in bone marrow-derived cells. Clin Orthop Relat Res. 2003;407:102–18.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag London Limited 2011

Authors and Affiliations

  • Rozalia I. Dimitriou
    • 1
  • Nikolaos K. Kanakaris
    • 1
  • Peter V. Giannoudis
    • 2
  1. 1.Department of Trauma and Orthopaedic SurgeryLeeds Teaching Hospitals NHS TrustLeedsUK
  2. 2.Academic Department of Trauma and Orthopaedic Surgery, School of MedicineUniversity of LeedsLeedsUK

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