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Hematologic and Lymphoid Neoplasia

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Serous Effusions

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Abstract

Serous effusions are commonly seen in lymphomas, in about 20–30% of cases, and are less frequently seen with myeloid malignancy.1,2 In children, effusions are more commonly associated with lymphoma and leukemia than with other malignancies.3 Most effusions are secondary, and are caused by direct infiltration with leukemia or lymphoma from an adjacent disease location, by obstruction of the lymphatic system draining the body cavity by lymphoma or by infection secondary to immune depression due to extensive marrow involvement or secondary to the treatment of lymphoma or leukemia. In addition, effusions may also be caused by inflammation following direct damage by radiation, chemotherapy, and novel tyrosine-kinase inhibitors such as dasatinib or by graft versus host disease in the case of bone marrow transplantation for the malignancy.4–6 In this section, only serous effusions arising from direct lymphoma or leukemia infiltration of a body cavity will be discussed.

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Author information

Authors and Affiliations

  1. Department of Pathology, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway

    Anne M. Tierens M.D., Ph.D.

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  1. Anne M. Tierens M.D., Ph.D.
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Correspondence to Anne M. Tierens M.D., Ph.D. .

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Editors and Affiliations

  1. , Department of Pathology, The Norwegian Radium Hospital, Oslo, 0310, Norway

    Ben Davidson

  2. , İstanbul Faculty of Medicine, İstanbul University, İstanbul, Turkey

    Pinar Firat

  3. , Department of Pathology, The University of Michigan, Ann Arbor, 48109, USA

    Claire W. Michael

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© 2012 Springer-Verlag London Limited

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Tierens, A.M. (2012). Hematologic and Lymphoid Neoplasia. In: Davidson, B., Firat, P., Michael, C. (eds) Serous Effusions. Springer, London. https://doi.org/10.1007/978-0-85729-697-9_6

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  • DOI: https://doi.org/10.1007/978-0-85729-697-9_6

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  • Publisher Name: Springer, London

  • Print ISBN: 978-0-85729-696-2

  • Online ISBN: 978-0-85729-697-9

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