Malignant Mesothelioma



Malignant mesothelioma (MM) is a primary tumor of the serous cavities and is connected to asbestos exposure. The most frequent location for MM is the pleura, followed by the peritoneum, pericardium and tunica vaginalis testis. The development of MM occurs after a long latency period, typically 20–40 years from the time of initial asbestos exposure to diagnosis, suggesting that multiple genetic events are required for tumorigenic conversion of mesothelial cells. Characteristically, MM are highly heterogeneous in terms of differentiation, which is also mirrored in variable biological behavior and prognosis.


Mesothelial Cell Malignant Mesothelioma Asbestos Exposure Asbestos Fiber Mesothelioma Cell 
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Copyright information

© Springer-Verlag London Limited 2012

Authors and Affiliations

  1. 1.Department of Laboratory Medicine, Division of PathologyKarolinska InstitutetStockholmSweden

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