Miscellaneous Specimens and Ancillary Techniques
This chapter refers to miscellaneous specimens – needle core biopsies, fine needle aspirates, cytospins, liquid-based cytology, and cell blocks. Aids to macroscopic description and dissection such as specimen photography and radiography and intraoperative frozen section assessment are considered. Key ancillary techniques now playing an essential role in diagnosis, prognosis, and management decisions are highlighted. These include immunohistochemistry, immunofluorescence, flow cytometry, in situ hybridization, electron microscopy, and molecular genetic analysis.
KeywordsCore Biopsy Needle Core Biopsy Malignant Mesothelioma Small Biopsy Multidisciplinarian Team Meeting
- Human tissue and biological samples for use in research: operational and ethical guidelines. Medical Research Council, London. 2001. http://www.mrc.ac.uk/pdf-tissue_guide_fin.pdf. Accessed on November 2002
- Lester SC. Chapter 6. Operating Room Consultations. In: Manual of Surgical Pathology. 3rd ed. Philadelphia: Churchill Livingstone; 2007.Google Scholar
- McKay B. Electron microscopy in tumour diagnosis. In: Fletcher CDM, editor. Diagnostic Histopathology of Tumours, vol. 2. 3rd ed. London: Churchill Livingstone; 2007. p. 1831–59.Google Scholar
- Swerdlow SH, Compo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW. WHO Classification of Tumours. Pathology and Genetics. Tumours of Haemopoietic and Lymphoid Tissues. Lyon: IARC Press; 2008.Google Scholar