Lymph Nodes, Spleen, and Bone Marrow

  • Lakshmi Venkatraman
  • Damian T. McManus


This chapter outlines the anatomy, clinical presentation, and relevant clinical investigations. Details of both non-neoplastic and neoplastic pathological conditions affecting this organ site are given. Clinical considerations in obtaining the diagnostic biopsy and therapeutic resection specimens are outlined, with details of their handling and dissection in the histopathology laboratory. This is correlated with relevant histopathology reports, giving summary of core prognostic and patient management items. Current WHO and TNM classifications are referenced.


Anaplastic Large Cell Lymphoma Hairy Cell Leukemia White Pulp Megaloblastic Anemia Trephine Biopsy 
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Copyright information

© Springer-Verlag London 2013

Authors and Affiliations

  1. 1.Histopathology LaboratoryInstitute of Pathology, Royal Victoria Hospital, Belfast Health and Social Care TrustBelfastUK
  2. 2.Histopathology LaboratoryBelfast City Hospital, Belfast Health and Social Care TrustBelfastUK

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