Abstract
This chapter outlines the anatomy, clinical presentation, and relevant clinical investigations. Details of both non-neoplastic and neoplastic pathological conditions affecting this organ site are given. Clinical considerations in obtaining the diagnostic biopsy and therapeutic resection specimens are outlined, with details of their handling and dissection in the histopathology laboratory. This is correlated with relevant histopathology reports, giving summary of core prognostic and patient management items. Current WHO and TNM classifications are referenced.
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Bibliography
Allen DC, Cameron RI. Histopathology specimens: clinical, pathological and laboratory aspects. 1st ed. Berlin-Heidelberg: Springer; 2004.
Alizadeh AA, Eisen MB, Davis RE. Distinct types of large B-cell lymphoma identified by gene expression profiling. Nature. 2000;403:503–11.
Braunwald E, Fauci AS, Kasper DL, Hauser SL, Longo DL, Jameson JL, editors. Harrison’s principles of internal medicine, vol. 1. 17th ed. New York: McGraw-Hill; 2008. p. 353–68.
Adamson JW, Longo DL. Anaemia and polycythemia.
Konkle BA. Bleeding and thrombosis.
Henry PH, Longo DL. Enlargement of the lymph nodes and spleen.
Holland SM, Gallin JI. Disorders of granulocytes and monocytes.
Brown D, Gatter K, Natkunam Y. Bone marrow diagnosis: an illustrated guide. Oxford: Wiley Blackwell; 2006.
Brunning RD, Arber DA. Bone marrow. Chapter 23. In: Rosai J, editor. Rosai and Ackerman’s surgical pathology. 10th ed. St. Louis: Elsevier; 2011.
Chan JKC. Tumours of the lymphoreticular system, including spleen and thymus. In: Fletcher CDM, editor. Diagnostic histopathology of tumours, vol. 2. 3rd ed. London: Harcourt; 2007. p. 1139–310.
Hall JG. The functional anatomy of lymph nodes. In: Stansfield AG, d’ Ardenne AJ, editors. Lymph node biopsy interpretation. 2nd ed. Edinburgh: Churchill Livingstone; 1992. p. 3–28.
O’Malley DP, George TI, Orazi A, editors. Benign and reactive conditions of lymph node and spleen. Washington DC: ARP Press; 2009.
Rosai J. Lymph nodes, spleen. Chapter 22. In: Rosai J, editor. Rosai and Ackerman’s surgical pathology. 10th ed. St. Louis: Elsevier; 2011.
Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW. WHO classification of tumours. Pathology and genetics. Tumours of haemopoietic and lymphoid tissues. Lyon: IARC Press; 2008.
The Royal College of Pathologists. Minimum dataset for the histopathological reporting of lymphoma and tissue pathways for lymph node, spleen and bone marrow trephine biopsy specimens. Accessed at http://www.rcpath.org/index.asp?PageID=254. Accessed on December 2011.
Wilkins BS, Wright DH. Illustrated pathology of the spleen. Cambridge: Cambridge University Press; 2000. p. 1–31.
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Venkatraman, L., McManus, D.T. (2013). Lymph Nodes, Spleen, and Bone Marrow. In: Allen, D., Cameron, R. (eds) Histopathology Specimens. Springer, London. https://doi.org/10.1007/978-0-85729-673-3_45
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DOI: https://doi.org/10.1007/978-0-85729-673-3_45
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