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Lymphedema pp 471-475 | Cite as

Etiology and Pathophysiology

  • Waldemar L. Olszewski
Chapter

Abstract

Lymphatic filariasis is caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori. 1,2 The adult worms live in the lymphatic vessels and are responsible for the primary lesions causing lymph stasis. Lymph stasis predisposes to bacterial infections and host inflammatory response. Adult worms die after some time, but bacterial colonization of tissues continues. The pathological changes in tissues develop further, leading to an increase in limb volume, hyperkeratosis, and fibrosis.

Keywords

Adult Worm Lymphatic Filariasis Spermatic Cord Host Inflammatory Response Limb Volume 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag London Limited 2011

Authors and Affiliations

  • Waldemar L. Olszewski
    • 1
  1. 1.Department of Surgical Research and TransplantologyMedical Research CentreWarsawPoland

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