Lymphedema pp 471-475 | Cite as

Etiology and Pathophysiology

  • Waldemar L. Olszewski


Lymphatic filariasis is caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori. 1,2 The adult worms live in the lymphatic vessels and are responsible for the primary lesions causing lymph stasis. Lymph stasis predisposes to bacterial infections and host inflammatory response. Adult worms die after some time, but bacterial colonization of tissues continues. The pathological changes in tissues develop further, leading to an increase in limb volume, hyperkeratosis, and fibrosis.


Adult Worm Lymphatic Filariasis Spermatic Cord Host Inflammatory Response Limb Volume 
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Copyright information

© Springer-Verlag London Limited 2011

Authors and Affiliations

  • Waldemar L. Olszewski
    • 1
  1. 1.Department of Surgical Research and TransplantologyMedical Research CentreWarsawPoland

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