Early Diagnosis in Latent Phase
Lymphedema is typically characterized by the time of onset (staging) and the severity of the symptoms (grading). Various staging schemes have been proposed, but increasingly most use a four-stage scale: stage 0, a latent or subclinical phase when swelling is not evident, although lymphatic insufficiency is presumed; stage I, accumulation of tissue fluid that generally resolves with elevation of the affected limb with minimal swelling (<20% increase); stage II, when elevation fails to reduce a moderate amount of swelling (20–40% increase) and pitting edema is present; and stage III, irreversible, severe (>40% increase) swelling is present and the tissue is fibrotic.
KeywordsLatent Phase Lymphatic Function Water Displacement Staging Scheme Minimal Detectable Change
Statement of Conflict of Interest
L.C. Ward has consulted for ImpediMed Ltd. ImpediMed Ltd. had no involvement, financial or otherwise, in the conception and execution of this study or in the preparation of the manuscript.
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