Surgical Site Infection Prophylaxis

  • Amish Ajit Dangodara


Surgical site infection (SSI) is one of the most common hospital-acquired infections, occurring in up to 5% of clean extra-abdominal surgeries and in up to 20% of intraabdominal surgeries.1 It is defined as an infection at the site of surgery that occurs within 30 days after surgery or within 1 year if a foreign body was implanted during surgery. Although there are a number of patient-specific risk factors, the type of surgery is the primary risk factor and determines the need for prophylactic antibiotics. This chapter reviews the risk factors and recommendations for antibiotic prophylaxis to reduce SSI. Other prophylactic measures to prevent endocarditis, pneumonia, and aspiration are covered elsewhere.


Surgical Site Infection Antibiotic Prophylaxis Prophylactic Antibiotic Primary Risk Factor Chlorhexidine Gluconate 
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Copyright information

© Springer-Verlag London Limited 2011

Authors and Affiliations

  1. 1.UCI Medical Center, UCI Hospitalist ProgramUniversity of California, Irvine, College of MedicineOrangeUSA

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