Prevention of Infective Endocarditis (Bacterial Endocarditis Prophylaxis)



It is thought to result from formation of nonbacterial thrombotic endocarditis (platelets and fibrin) on the surface of a valve or endothelial surface from mechanical disruption or inflammation, bacteremia, bacterial adherence to the fibrin–platelet matrix, and proliferation of the bacteria within the vegetation.


Infective Endocarditis Rheumatic Heart Disease Mitral Valve Prolapse Cardiac Condition Antimicrobial Prophylaxis 


  1. 1.
    Oliver R, Roberts GJ, Hooper L, Worthington HV. Antibiotics for the prophylaxis of bacterial endocarditis in dentistry. Cochrane Database Syst Rev. 2008; (4):CD003813.Google Scholar
  2. 2.
    Wilson W, Taubert KA, Gewitz M, et al. Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation. 2007;116(15):1736-1754.PubMedCrossRefGoogle Scholar
  3. 3.
    Habib G, Hoen B, Tornos P, et al. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the task force on the prevention, diagnosis, and treatment of infective endocarditis of the European Society of Cardiology (ESC). Eur Heart J. 2009;30(19):2369-2413.PubMedCrossRefGoogle Scholar
  4. 4.
    Gould FK, Elliott TS, Foweraker J, et al. Guidelines for the prevention of endocarditis: report of the Working Party of the British Society for Antimicrobial Chemotherapy. J Antimicrob Chemother. 2006;57(6):1035-1042.PubMedCrossRefGoogle Scholar
  5. 5.
    Richey R, Wray D, Stokes T. Prophylaxis against infective endocarditis: summary of NICE guidance. BMJ. 2008;336(7647):770-771.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag London Limited 2011

Authors and Affiliations

There are no affiliations available

Personalised recommendations