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Renal Failure, Dialysis and Transplantation: In the Management of Renal Cell Carcinoma (Solitary Kidney and Bilateral Renal Tumours)

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Urological Oncology
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Abstract

The aim of this chapter is to summarize the renal problems encountered in the management of adult genito-urinary cancers. Maintenance of renal function is crucial in the management of most malignancies including genitourinary cancer as optimal renal function is necessary for multimodal cancer therapy. There are a number of scenarios when either renal function is likely to be compromised as a result of cancer itself (e.g. Bilateral obstruction of ureters), treatment (following chemotherapy or surgery) and occasionally long time after the treatment (Retroperitoneal fibrosis).

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References

  1. Bankir L, Trinh-Trang-Tan M-M. Urea and the kidney. In: Breener BM, editor. Brenner and Rector’s kidney. 6th ed. Philadelphia: WB Saunders; 2000. p. 637–79.

    Google Scholar 

  2. Levey AS, Perrone RD, Madias NE. Serum creatinine and renal function. Annu Rev Med. 1988;39:465–90.

    Article  CAS  PubMed  Google Scholar 

  3. Doolan PD, Alpen EL, Theil GB. A clinical appraisal of the plasma concentration and endogenous clearance of creatinine. Am J Med. 1962;32:65–79.

    Article  CAS  PubMed  Google Scholar 

  4. Levy AS, Madaio MP, Perrone RD. Laboratory assessment of renal disease: clearance, analysis and biopsy. In: Brenner BM, Rector FC, editors. The kidney. 4th ed. Philadelphia: WB Saunders; 1991. p. 919–68.

    Google Scholar 

  5. Position statement: chronic kidney disease and automatic reporting of estimated glomerular filtration rate. Med J Aust. 2005;183:138–41.

    Google Scholar 

  6. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16:31–41.

    Article  CAS  PubMed  Google Scholar 

  7. Levey AS, Bosch JP, Lewis JB, et al. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med. 1999;130:461–70.

    Article  CAS  PubMed  Google Scholar 

  8. Poole SG, Dooley MJ, Rischin D. A comparison of bedside renal function estimates and measured glomerular filtration rate (Tc99m DTPA clearance) in cancer patients. Ann Oncol. 2002;13:949–55.

    Article  CAS  PubMed  Google Scholar 

  9. Peters AM. Quantification of renal haemodynamics with radionuclides. Eur J Nucl Med. 1991;18(4):274–86.

    Article  CAS  PubMed  Google Scholar 

  10. NKF-DOQI clinical practice guidelines for hemodialysis adequacy. National Kidney Foundation. Am J Kidney Dis. 1997;30(3 Suppl 2):S15–66.

    Google Scholar 

  11. Stahl RAK, Löw I, Schoeppe W. Progressive renal failure in a patient after one and two-thirds nephrectomy. J Mol Med. 1988;66:508–10.

    CAS  Google Scholar 

  12. Abdi R, Dong VM, Rubel JR, et al. Correlation between glomerular size and long-term renal function in patients with substantial loss of renal mass. J Urol. 2003;170(1):42–4.

    Article  PubMed  Google Scholar 

  13. Solomon R, Werner C, Mann D, D’Elia J, Silva P. Effects of saline, mannitol, and frusemide to prevent acute decreases in renal function induced by radiocontrast agents. N Engl J Med. 1994;331:1416–20.

    Article  CAS  PubMed  Google Scholar 

  14. Novick AC, Derweesh I. Open partial nephrectomy for renal tumours: current status. BJU Int. 2005;95 Suppl 2:35–40.

    Article  PubMed  Google Scholar 

  15. Novick AC. Renal hypothermia: in vivo and ex vivo. Urol Clin North Am. 1983;10:637–44.

    CAS  PubMed  Google Scholar 

  16. Secin FP, Carver B, Kattan M, Eastham JA. Current recommendations for delaying renal transplantation after localizedprostate cancer treatment: are they still appropriate? Transplantation. 2004;78:710–2.

    Article  PubMed  Google Scholar 

  17. Kasiske BL, Cangro CB, Hariharan S, et al. The evaluation of renal transplantation candidates: clinical practice guidelines. Am J Transplant. 2001;1 Suppl 2:3–95.

    PubMed  Google Scholar 

  18. Maisonneuve P, Agodoa L, Gellert R, et al. Cancer in patients on dialysis for end-stage renal disease: an international collaborative study – group of 3. Lancet. 1999;354:93–9.

    Article  CAS  PubMed  Google Scholar 

  19. Stewart JH, Buccianti G, Agodoa L, et al. Cancers of the kidney and urinary tract in patients on dialysis for end-stage renal disease: analysis of data from the United States, Europe, and Australia and New Zealand. J Am Soc Nephrol. 2003;14:197–207.

    Article  PubMed  Google Scholar 

  20. Doublet JD, Peraldi MN, Gattegno B, Thibault P, Sraer JD. Renal cell carcinoma of native kidneys: prospective study of 129 renal transplant patients. J Urol. 1997;158(1):42–4.

    Article  CAS  PubMed  Google Scholar 

  21. Truong LD, Krishnan B, Cao JT, Barrios R, Suki WN. Renal neoplasm in acquired cystic disease. Am J Kidney Dis. 1995;26:1–12.

    Article  CAS  PubMed  Google Scholar 

  22. Bokemeyer C, Thon WF, Brunkhorst T, et al. High frequency of urothelial cancers in patients with kidney transplantations for end-stage analgesic nephropathy. Eur J Cancer. 1996;32A(1):175–6.

    Article  CAS  PubMed  Google Scholar 

  23. Weld JK, Landman J. Comparison of cryoablation, radiofrequency ablation, land HIFU for treating small renal tumours. BJU Int. 2005;96:1224–9.

    Article  PubMed  Google Scholar 

  24. Darmon M, Ciroldi M, Thiery G, et al. Clinical review: specific aspects of acute renal failure in cancer patients. Crit Care. 2006;10:211 (Epub: Published ahead of print).

    Article  PubMed Central  PubMed  Google Scholar 

  25. Murray MD, Brater DC. Renal toxicity of the nonsteroidal anti-inflammatory drugs. Ann Rev Pharmacol Toxicol. 1993;32:4350–65.

    Google Scholar 

  26. Gutthann SP, Rodriguez LAG, Raiford DS, Oliart AD, Romeu JR. Non-steroidal anti-inflammatory drugs and the risk of hospitalization for acute renal failure. Arch Int Med. 1996;156:2433–9.

    Article  CAS  Google Scholar 

  27. Pentheroudakis G, O’Neill VJ, Vasey P, Kaye SB. Spontaneous acute tumour lysis syndrome in patients with metastatic germ cell tumours. Report of two cases. Support Care Cancer. 2001;9(7):554–7.

    Article  CAS  PubMed  Google Scholar 

  28. Myers BD, Moran SM. Hemodynamically mediated acute renal failure. N Eng J Med. 1986;314:97–105.

    Article  CAS  Google Scholar 

  29. Arany I, Safirstein RL. Cisplatin nephrotoxicity. Semin Nephrol. 2003;23:460–4.

    Article  CAS  PubMed  Google Scholar 

  30. Ries F, Klastersky J. Nephrotoxicity induced by cancer chemotherapy with special emphasis on cisplatin toxicity. Am J Kidney Dis. 1986;8:368–79.

    Article  CAS  PubMed  Google Scholar 

  31. Condit PT, Chanes RE, Joel W. Renal toxicity of methotrexate. Cancer. 1969;23:126–31.

    Article  CAS  PubMed  Google Scholar 

  32. Wall SM, et al. Effective clearance of methotrexate using high-flux hemodialysis membranes. Am J Kidney Dis. 1996;28:846–54.

    Article  CAS  PubMed  Google Scholar 

  33. Walker RJ, Duggin GG. Drug nephrotoxicity. Annu Rev Pharmacol Toxicol. 1988;28:331–45.

    Article  CAS  PubMed  Google Scholar 

  34. Nagai J, Takano M. Review: Molecular aspects of renal handling of aminoglycosides and strategies for preventing the nephrotoxicity. Drug Metab Pharmacokin. 2004;19:159–70.

    Article  CAS  Google Scholar 

  35. Bieniasz M, Damogala P, Kwiatkowski A, et al. The assessment of residual kidney function after living donor nephrectomy. Transplant Proc. 2009;41:91–2.

    Article  CAS  PubMed  Google Scholar 

  36. Donckerwolcke RM, Coppes MJ. Adaptation of renal function after unilateral nephrectomy in children with renal tumours. Pediatr Nephrol. 2001;16:568–74.

    Article  CAS  PubMed  Google Scholar 

  37. Chapman D, Moore R, Klarenbach S, Braam B. Residual renal function after partial or radical nephrectomy for renal cell carcinoma. Can Urol Assoc J. 2010;4(5):337–43.

    PubMed Central  PubMed  Google Scholar 

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Correspondence to Raj Thuraisingham MD, FRCP .

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Thuraisingham, R. (2015). Renal Failure, Dialysis and Transplantation: In the Management of Renal Cell Carcinoma (Solitary Kidney and Bilateral Renal Tumours). In: Nargund, V., Raghavan, D., Sandler, H. (eds) Urological Oncology. Springer, London. https://doi.org/10.1007/978-0-85729-482-1_9

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  • DOI: https://doi.org/10.1007/978-0-85729-482-1_9

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