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Diabetes and Frailty

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Diabetes Care for the Older Patient

Abstract

It is apparent that some individuals age more rapidly and become frailer, while others remain robust and physically independent well into their tenth decade. Frailty is a term intuitively understood, but its definition presents a challenge and there is no clear consensus. It is believed to relate to the decrease in physiological reserve and diminished ability to resist stressors, promoting vulnerability in the frail individual. Currently a range of models are used to measure frailty but the choice of components of the model is critical to any definition.

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References

  1. Drey M, Pfeifer K, Sieber CC, Bauer JM. The fried frailty criteria as inclusion criteria for a randomized controlled trial: personal experience and literature review. Gerontology 2011;57:11–8.

    Article  PubMed  CAS  Google Scholar 

  2. Rockwood K, Mitnitski A. Frailty in relation to the accumulation of deficits. Journals of Gerontology Series A-Biological Sciences & Medical Sciences 2007;62:722–7.

    Google Scholar 

  3. Abellan van Kan G, Rolland Y, Houles M, Gillette-Guyonnet S, Soto M, Vellas B. The assessment of frailty in older adults. Clinics in Geriatric Medicine 2010;26:275–86.

    Google Scholar 

  4. Shoff SM, Klein R, Moss SE, Klein BE, Cruickshanks KJ. Weight change and glycemic control in a population-based sample of adults with older-onset diabetes. Journals of Gerontology Series A-Biological Sciences & Medical Sciences 1998;53:M27-32.

    Article  CAS  Google Scholar 

  5. Van der Does FE, De Neeling JN, Snoek FJ, Kostense PJ, Grootenhuis PA, Bouter LM, et al. Symptoms and well-being in relation to glycemic control in type II diabetes. Diabetes Care 1996;19:204–10.

    Article  PubMed  Google Scholar 

  6. Morley JE. Diabetes, sarcopenia, and frailty. Clinics in Geriatric Medicine 2008;24:455–69.

    Article  PubMed  Google Scholar 

  7. Tsuji I, Whalen S, Finucane TE. Predictors of nursing home placement in community-based long-term care. Journal of the American Geriatrics Society 1995;43:761–6.

    PubMed  CAS  Google Scholar 

  8. Aspray TJ, Nesbit K, Cassidy TP, Farrow E, Hawthorne G. Diabetes in British nursing and residential homes: a pragmatic screening study. Diabetes Care 2006;29:707–8.

    Article  PubMed  Google Scholar 

  9. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. UK Prospective Diabetes Study Group. BMJ 1998;317:703–13.

    Google Scholar 

  10. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet 1998;352:854–65.

    Google Scholar 

  11. Kannel WB, McGee DL. Diabetes and cardiovascular risk factors: the Framingham study. Circulation 1979;59:8–13.

    PubMed  CAS  Google Scholar 

  12. Court-Brown CM, Clement N. Four score years and ten: an analysis of the epidemiology of fractures in the very elderly. Injury 2009;40:1111–4.

    Article  PubMed  CAS  Google Scholar 

  13. Mayne D, Stout NR, Aspray TJ. Diabetes, falls and fractures. Age Ageing 2010;39:522–5.

    Article  PubMed  Google Scholar 

  14. Nordin E, Lindelof N, Rosendahl E, Jensen J, Lundin-Olsson L. Prognostic validity of the Timed Up-and-Go test, a modified Get-Up-and-Go test, staff’s global judgement and fall history in evaluating fall risk in residential care facilities. Age Ageing 2008;37:442–8.

    Article  PubMed  Google Scholar 

  15. Berlie HD, Garwood CL. Diabetes medications related to an increased risk of falls and fall-related morbidity in the elderly. Ann Pharmacother 2010;44:712–7.

    Article  PubMed  CAS  Google Scholar 

  16. Nelson JM, Dufraux K, Cook PF. The relationship between glycemic control and falls in older adults. Journal of the American Geriatrics Society 2007;55:2041–4.

    Article  PubMed  Google Scholar 

  17. Rakel A, Sheehy O, Rahme E, LeLorier J. Osteoporosis among patients with type 1 and type 2 diabetes. Diabetes Metab 2008;34:193–205.

    Article  PubMed  CAS  Google Scholar 

  18. Barton SH, Murray JA. Celiac disease and autoimmunity in the gut and elsewhere. Gastroenterol Clin North Am 2008;37:411–28, vii.

    Article  PubMed  Google Scholar 

  19. Leese GP, Flynn RV, Jung RT, Macdonald TM, Murphy MJ, Morris AD. Increasing prevalence and incidence of thyroid disease in Tayside, Scotland: the Thyroid Epidemiology Audit and Research Study (TEARS). Clin Endocrinol (Oxf) 2008;68:311–6.

    CAS  Google Scholar 

  20. Molbak AG, Christau B, Marner B, Borch-Johnsen K, Nerup J. Incidence of insulin-dependent diabetes mellitus in age groups over 30 years in Denmark. Diabet Med 1994;11:650–5.

    Article  PubMed  CAS  Google Scholar 

  21. Kilvert A, Fitzgerald MG, Wright AD, Nattrass M. Clinical characteristics and aetiological classification of insulin-dependent diabetes in the elderly. Q J Med 1986;60:865–72.

    PubMed  CAS  Google Scholar 

  22. Wilkinson K, Martin IC, Gough MJ, Stewart JAD, Lucas SB, Freeth H, et al. An Age Old Problem- A review of the care received by elderly patients undergoing surgery. London: NCEPOD, 2010.

    Google Scholar 

  23. Gerstein HC, Haynes RB. Evidence-based diabetes care. Hamilton, Ont. ; London: BC Decker, 2001.

    Google Scholar 

  24. Wu P. Thyroid disorders and diabetes. It is common for a person to be affected by both thyroid disease and diabetes. Diabetes Self Manag 2007;24:80–2, 85–7.

    Google Scholar 

  25. Biondi B, Palmieri EA, Klain M, Schlumberger M, Filetti S, Lombardi G. Subclinical hyperthyroidism: clinical features and treatment options. Eur J Endocrinol 2005;152:1–9.

    Article  PubMed  CAS  Google Scholar 

  26. Randin JP, Tappy L, Scazziga B, Jequier E, Felber JP. Insulin sensitivity and exogenous insulin clearance in Graves’ disease. Measurement by the glucose clamp technique and continuous indirect calorimetry. Diabetes 1986;35:178–81.

    Article  PubMed  CAS  Google Scholar 

  27. Mooradian AD, Osterweil D, Petrasek D, Morley JE. Diabetes mellitus in elderly nursing home patients. A survey of clinical characteristics and management. J Am Geriatr Soc 1988;36:391–6.

    PubMed  CAS  Google Scholar 

  28. Slowikowski GC, Funk M. Factors associated with pressure ulcers in patients in a surgical intensive care unit. J Wound Ostomy Continence Nurs 2010;37:619–26.

    Article  PubMed  Google Scholar 

  29. Martikainen P, Valkonen T. Mortality after the death of a spouse: rates and causes of death in a large Finnish cohort. Am J Public Health 1996;86:1087–93.

    Article  PubMed  CAS  Google Scholar 

  30. Wittenberg R, Comas-Herrera A, Pickard L, Hancock R. Future demand for long-term care in the UK: A summary of projections of long-term care finance for older people to 2051. York, UK: The Joseph Rowntree Foundation, 2004.

    Google Scholar 

  31. Hirsch D. Paying for long-term care: Moving forward. York, UK: The Joseph Rowntree Foundation, 2006.

    Google Scholar 

  32. Diabetes UK. Good clinical practice guidelines for care home residents with diabetes. London: Diabetes UK, 2010:111.

    Google Scholar 

  33. Aspray TJ, Nesbit K, Cassidy TP, Hawthorne G. Rapid assessment methods used for health-equity audit: diabetes mellitus among frail British care-home residents. Public Health 2006;120:1042–51.

    Article  PubMed  Google Scholar 

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© 2011 Springer-Verlag London Limited

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Smith, G.M., Aspray, T.J. (2011). Diabetes and Frailty. In: Hawthorne, G. (eds) Diabetes Care for the Older Patient. Springer, London. https://doi.org/10.1007/978-0-85729-461-6_6

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  • DOI: https://doi.org/10.1007/978-0-85729-461-6_6

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  • Publisher Name: Springer, London

  • Print ISBN: 978-0-85729-460-9

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