Pregnancy and Rheumatic Diseases

  • Maurice Barry


  • If a patient tells you she has become pregnant or is considering pregnancy, ask the rheumatologist to see her

  • Female patients on methotrexate, leflunomide or cyclophosphamide should not attempt to become pregnant; a male patient should not attempt to father a child. The drugs are potentially teratogenic

  • Women on biologic agents (e.g. etanercept, anakinra, infliximab) should use adequate contraception as the effects on the foetus are unknown

  • Sulfasalazine, methotrexate and azathioprine may reduce the sperm count and thus fertility

  • Women with active inflammatory arthritis appear less likely to become pregnant that than those whose arthritis is inactive

  • Those starting cyclophosphamide should consider sperm or ovum banking


Public Health Rheumatoid Arthritis General Practice Female Patient Male Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer-Verlag London 2003

Authors and Affiliations

  • Maurice Barry
    • 1
  1. 1.James Connolly Memorial HospitalDublinIreland

Personalised recommendations