Substance Prioritisation for the Development of EU Acute Exposure Toxicity Thresholds: Risk-Informed Decision Making

  • Mary Trainor
  • Ron Macbeth
  • Peter Ridgway
Conference paper


The aim of the EU ACUTEX project is to develop a methodology for establishing European Acute Exposure Threshold Levels (EU AETLs) for toxic substances in relation to harm to people by inhalation. Their development is initially in the context of the EU’ seveso II’ Directive through which the risks of major accidents from chemical sites are regulated. This paper describes the prioritisation of 21 substances for AETL case studies based on an EU stakeholder consultation exercise. It also outlines progress on the subsequent development of a prioritisation methodology to inform initial substance selection for a possible further AETLs programme.


Competent Authority Risk Governance Priority Substance Major Accident Chemical Site 


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Copyright information

© Springer-Verlag London 2004

Authors and Affiliations

  • Mary Trainor
    • 1
  • Ron Macbeth
    • 1
  • Peter Ridgway
    • 2
  1. 1.Helen Balmforth Health & Safety LaboratorySheffieldUK
  2. 2.Health & Safety ExecutiveBootleUK

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