Abstract
There is an increasing awareness and concern about the importance of ethics in both the practice of medicine and research. In particular, biomedical/surgical research – which involves the search for new technologies, techniques, and therapies – is frequently at the center of ethical issues. In fact, ethical issues are often at the forefront of both clinical and basic science research. Ethical concerns around clinical research include informed consent, respect for autonomy, acceptable risk-benefit ratio, and ensuring that the research is scientifically rigorous enough to justify human subject involvement.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Markel H. Experiments and observations: how William Beaumont and Alexis St. Martin seized the moment of scientific progress. JAMA. 2009;302:804-806.
Fost N, Levine RJ. The dysregulation of human subject research. JAMA. 2007;298:2196-2198.
The Nuremberg Code. JAMA 1996;276:1691.
World Medical Association declaration of Helsinki. Recommendations guiding physicians in biomedical research involving human subjects. JAMA. 1997;277:925-926.
McCallum JM, Arekere DM, Green BL, et al. Awareness and knowledge of the U.S. Public Health Service syphilis study at Tuskegee: implications for biomedical research. J Health Care Poor Underserved. 2006;17:716-733.
Goliszek A. In the Name of Science. New York: St. Martin’s Press; 2003.
Services UDoHaH. Protections of human subjects, 45 CFR 46. 1991.
Skolnick BE. Ethical and institutional review board issues. Adv Neurol. 1998;76:253-262.
Weijer C, Dickens B, Meslin EM. Bioethics for clinicians: 10. Research ethics. CMAJ. 1997;156:1153-1157.
Emanuel EJ, Wendler D, Grady C. What makes clinical research ethical? JAMA. 2000;283:2701-2711.
McKneally MF, Ignagni E, Martin DK, D’Cruz J. The leap to trust: perspective of cholecystectomy patients on informed decision making and consent. J Am Coll Surg. 2004;199:51-57.
Biffl WL, Spain DA, Reitsma AM, et al. Responsible development and application of surgical innovations: a position statement of the Society of University Surgeons. J Am Coll Surg. 2008;206:1204-1209.
Jones JW. Ethics of rapid surgical technological advancement. Ann Thorac Surg. 2000;69:676-677.
Resnik D. The Ethics of Science: An Introduction. New York: Routledge; 1998.
National Academy of Sciences NAoE, Institute of Medicine. Responsible Science: Ensuring the Integrity of the Research Process. Washington, D.C.: National Academy Press; 1992.
Morin K, Rakatansky H, Riddick FA Jr, et al. Managing conflicts of interest in the conduct of clinical trials. JAMA. 2002;287:78-84.
Thompson DF. Understanding financial conflicts of interest. N Engl J Med. 1993;329:573-576.
International Committee of Medical Journal Editors. Uniform requirements for manuscripts submitted to biomedical journals. JAMA. 1993;269:2282-2286.
Pawlik TM, Platteborze N, Souba WW. Ethics and surgical research: what should guide our behavior? J Surg Res. 1999;87:263-269.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer-Verlag London Limited
About this chapter
Cite this chapter
Pawlik, T.M., Schwarze, M.L. (2011). Ethics in Surgical Research. In: Chen, H., Kao, L. (eds) Success in Academic Surgery. Springer, London. https://doi.org/10.1007/978-0-85729-313-8_4
Download citation
DOI: https://doi.org/10.1007/978-0-85729-313-8_4
Published:
Publisher Name: Springer, London
Print ISBN: 978-0-85729-312-1
Online ISBN: 978-0-85729-313-8
eBook Packages: MedicineMedicine (R0)