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Methods in Bone Histomorphometry for Animal Models

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Abstract

Animal models are essential for preclinical skeletal research, notably in the study of physiopathology of metabolic bone diseases as well as in the evaluation of a test agent for the prevention and treatment of bone diseases such as osteoporosis. However, rat or mouse models do not completely reflect human bone disorders and therapeutic responses, but they provide insight into the understanding of bone pathologies and their treatments.

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Acknowledgment

We are grateful to Claire Deschênes for her excellent technical assistance.

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Authors and Affiliations

  1. Laboratory of Metabolic Bone Diseases, CRCHUM – Hôpital Saint-Luc, Montréal, Québec, Canada

    Louis-Georges Ste-Marie

Authors
  1. Natalie Dion
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  2. Audray Fortin
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  3. Louis-Georges Ste-Marie
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Corresponding author

Correspondence to Louis-Georges Ste-Marie .

Editor information

Editors and Affiliations

  1. Nepean Hospital, Dept. Geriatric Medicine, University of Sydney, Penrith, 2750, New South Wales, Australia

    Gustavo Duque

  2. Department of Bone & Joint Disease, National Center for Geriatrics & Geronto, Obu-Aichi, Japan

    Ken Watanabe

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© 2011 Springer-Verlag London Limited

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Dion, N., Fortin, A., Ste-Marie, LG. (2011). Methods in Bone Histomorphometry for Animal Models. In: Duque, G., Watanabe, K. (eds) Osteoporosis Research. Springer, London. https://doi.org/10.1007/978-0-85729-293-3_4

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  • DOI: https://doi.org/10.1007/978-0-85729-293-3_4

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  • Publisher Name: Springer, London

  • Print ISBN: 978-0-85729-292-6

  • Online ISBN: 978-0-85729-293-3

  • eBook Packages: MedicineMedicine (R0)

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