Other Large Animal Models



Osteoporosis is a disease characterized by low bone mass and micro-architectural deterioration of bone tissue leading to skeletal fragility. Guidelines established by the United States Food and Drug Administration (FDA) stipulate that therapeutic treatments formulated to attenuate or prevent postmenopausal osteoporosis should, in the first instance, be evaluated in an ovariectomized (OVX) rodent such as the rat.


Bone Mineral Density Bone Loss Large Animal Model Areal Bone Mineral Density Postmenopausal Bone Loss 
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Copyright information

© Springer-Verlag London Limited 2011

Authors and Affiliations

  1. 1.Department of Anatomy and Cell BiologyIndiana University School of MedicineIndianapolisUSA

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