Laser/Light Applications in Urology

  • Nathaniel M. Fried
  • Brian R. Matlaga


Summary of laser-tissue interactions in urology.

Holmium:YAG and FREDDY laser lithotripsy.

Laser treatment of benign prostatic hyperplasia using high-power Holmium:YAG and KTP (Greenlight) lasers.

Laser incision of urethral and ureteral strictures.

Other laser applications in urology for treatment of penile carcinoma, partial nephrectomy, tissue welding,…etc.


Benign Prostatic Hyperplasia Partial Nephrectomy Holmium Laser Ureteral Stricture Laser Lithotripsy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Mulvaney WP, Beck CW. The laser beam in urology. J Urol. 1968;99:112-115.PubMedGoogle Scholar
  2. 2.
    Watson GM, Wickham JE. Initial experience with a pulsed dye laser for ureteric calculi. Lancet. 1986;1:1357-1358.PubMedCrossRefGoogle Scholar
  3. 3.
    Chan KF, Vassar GJ, Pfefer TJ, et al. Holmium:YAG laser lithotripsy: a dominant photothermal ablative mechanism with chemical decomposition of urinary calculi. Lasers Surg Med. 1999;25:22-37.PubMedCrossRefGoogle Scholar
  4. 4.
    Santa-Cruz RW, Leveillee RJ, Krongrad A. Ex vivo comparison of four lithotripters commonly used in the ureter: what does it take to perforate? J Endourol. 1998;12:417-422.PubMedCrossRefGoogle Scholar
  5. 5.
    Yates J, Zabbo A, Pareek G. A comparison of the FREDDY and holmium lasers during ureteroscopic lithotripsy. Lasers Surg Med. 2007;39:637-640.PubMedCrossRefGoogle Scholar
  6. 6.
    Galvin DJ, Pearle MS. The contemporary management of renal and ureteric calculi. BJU Int. 2006;98:1283-1288.PubMedCrossRefGoogle Scholar
  7. 7.
    Watterson JD, Girvan AR, Cook AJ, et al. Safety and efficacy of holmium: YAG laser lithotripsy in patients with bleeding diatheses. J Urol. 2002;168:442-445.PubMedCrossRefGoogle Scholar
  8. 8.
    Nazif OA, Teichman JM, Glickman RD, Welch AJ. Review of laser fibers: a practical guide for urologists. J Endourol. 2004;18(9):818-829.PubMedCrossRefGoogle Scholar
  9. 9.
    Knudsen BE, Glickman RD, Stallman KJ, et al. Performance and safety of holmium: YAG laser optical fibers. J Endourol. 2005;19(9):1092-1097.PubMedCrossRefGoogle Scholar
  10. 10.
    Lee H, Kang HW, Teichman JMH, Oh J, Welch AJ. Urinary calculus fragmentation during Ho:YAG and Er:YAG lithotripsy. Lasers Surg Med. 2006;38:39-51.PubMedCrossRefGoogle Scholar
  11. 11.
    Fried NM. Thulium fiber laser lithotripsy: an in vitro analysis of stone fragmentation using a modulated 110-watt thulium fiber laser at 1.94 μm. Lasers Surg Med. 2005;37(1):53-58.PubMedCrossRefGoogle Scholar
  12. 12.
    Kuntz RM. Laser treatment of benign prostatic hyperplasia. World J Urol. 2007;25:241-247.PubMedCrossRefGoogle Scholar
  13. 13.
    Malek RS, Kuntzman RS, Barrett DM. High power potassium-­titanyl-phosphate laser vaporization prostatectomy. J Urol. 2000;163:1730-1733.PubMedCrossRefGoogle Scholar
  14. 14.
    Malek RS, Kuntzman RS, Barrett DM. Photoselective potassium-titanyl-phosphate laser vaporization of the benign obstructive prostate: observations on long-term outcomes. J Urol. 2005;174(4 Pt 1):1344-1348.PubMedCrossRefGoogle Scholar
  15. 15.
    Bachmann A, Ruszat R, Wyler S, et al. Photoselective vaporization of the prostate: the basel experience after 108 procedures. Eur Urol. 2005;47(6):798-804.PubMedCrossRefGoogle Scholar
  16. 16.
    Tan AH, Gilling PJ, Kennett KM, Frampton C, Westenberg AM, Fraundorfer MR. A randomized trial comparing holmium laser enucleation of prostate with transurethral resection of prostate for treatment of bladder outlet obstruction secondary to benign prostatic hyperplasia in large glands (40–200 grams). J Urol. 2003;170:1270-1274.PubMedCrossRefGoogle Scholar
  17. 17.
    Kuntz RM, Ahyai S, Lehrich K, Fayad A. Transurethral holmium laser enucleation of the prostate versus transurethral electrocautery resection of the prostate: a randomized prospective trial in 200 patients. J Urol. 2004;172(3):1012-1016.PubMedCrossRefGoogle Scholar
  18. 18.
    Kuntz RM, Lehrich K, Ahyai S. Transurethral holmium laser enucleation of the prostate compared with transvesical open prostatectomy: 18-month follow-up of a randomized trial. J Endourol. 2004;18(2):189-191.PubMedCrossRefGoogle Scholar
  19. 19.
    Wilson LC, Gilling PJ, Williams A, et al. A randomised trial comparing holmium laser enucleation versus transurethral resection in the treatment of prostates larger than 40 grams: results at 2 years. Eur Urol. 2006;50(3):569-573.PubMedCrossRefGoogle Scholar
  20. 20.
    Elzayat E, Habib E, Elhilali M. Holmium laser enucleation of the prostate in patients on anticoagulant therapy or with bleeding disorders. J Urol. 2006;175(4):1428-1432.PubMedCrossRefGoogle Scholar
  21. 21.
    Xia SJ, Zhuo J, Sun XW, Han BM, Shao Y, Zhang YN. Thulium laser versus standard transurethral resection of the prostate: a randomized prospective trial. Eur Urol. 2008;53(2):382-389.PubMedCrossRefGoogle Scholar
  22. 22.
    Bach T, Herrmann TR, Ganzer R, Burchardt M, Gross AJ. RevoLix vaporesection of the prostate: initial results of 54 patients with a 1-year followup. World J Urol. 2007;25(3):257-262.PubMedCrossRefGoogle Scholar
  23. 23.
    Fried NM. High-power laser vaporization of the canine prostate using a 110 W thulium fiber laser at 1.91 μm. Lasers Surg Med. 2005;36:52-56.PubMedCrossRefGoogle Scholar
  24. 24.
    Perez-Marrero R, Goldenberg SL, Shore N, et al. A phase I/II dose-escalation study to assess the safety, tolerability, and preliminary efficacy of transurethral photodynamic therapy with lemuteporfin in men with lower urinary tract symptoms due to benign prostatic hyperplasia. J Urol. 2005;173(4):421-422 (A1556).Google Scholar
  25. 25.
    Jordan GH, Schlossberg SM, Devine CJ. Surgery of the penis and urethra. In: Walsh PC, Retik AB, Vaughan ED, Wein AJ, eds. Campbell’s Urology, vol. 3. 7th ed. Philadelphia: WB Saunders; 1998:3341-3347.Google Scholar
  26. 26.
    Razdan S, Silberstein IK, Bagley DH. Ureteroscopic endoureterotomy. BJU Int. 2005;95(Suppl 2):94-101.PubMedCrossRefGoogle Scholar
  27. 27.
    Varkarakis IM, Inagaki T, Allaf ME, et al. Comparison of erbium:yttrium-aluminum-garnet and holmium:yttrium-aluminum-garnet lasers for incision of urethra and bladder neck in an in vivo porcine model. Urology. 2005;65(1):191-195.PubMedCrossRefGoogle Scholar
  28. 28.
    Munoz JA, Riemer JD, Hayes GB, Negus D, Fried NM. Er:YAG laser incision of urethral strictures: early clinical results. Proc SPIE. 2007;6424:64241F-64244F.CrossRefGoogle Scholar
  29. 29.
    Syed HA, Biyani CS, Bryan N, Brough SJ, Powell CS. Holmium:YAG laser treatment of recurrent superficial bladder carcinoma: initial clinical experience. J Endourol. 2001;15(6):625-627.PubMedCrossRefGoogle Scholar
  30. 30.
    Windahl T, Andersson SO. Combined laser treatment for penile carcinoma: results after long-term followup. J Urol. 2003;169(6):2118-2121.PubMedCrossRefGoogle Scholar
  31. 31.
    Marr L, Skoog SJ. Laser incision of ureterocele in the pediatric patient. J Urol. 2002;167:280-282.PubMedCrossRefGoogle Scholar
  32. 32.
    Crain DS, Miller OF, Smith LJ, Roberts JL, Ross EV. Transcutaneous laser hair ablation for management of intraurethral hair after hypospadias repair: initial experience. J Urol. 2003;170:1948-1949.PubMedCrossRefGoogle Scholar
  33. 33.
    Bukkapatnam R, Seigne J, Helal M. 1-step removal of encrusted retained ureteral stents. J Urol. 2003;170:1111-1114.PubMedCrossRefGoogle Scholar
  34. 34.
    Anderson JK, Baker MR, Lindberg H, Cadeddu JA. Large-volume laparoscopic partial nephrectomy using the potassium-titanyl-phosphate (KTP) laser in a survival porcine model. Eur Urol. 2007;51(3):749-754.PubMedCrossRefGoogle Scholar
  35. 35.
    Kirsch AJ, Cooper CS, Gatti J, et al. Laser tissue soldering for hypospadias repair: results of a controlled prospective clinical trial. J Urol. 2001;165(2):574-577.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag London Limited 2011

Authors and Affiliations

  1. 1.Department of Physics and Optical ScienceUniversity of North CarolinaCharlotteUSA
  2. 2.Department of UrologyJohns Hopkins UniversityBaltimoreUSA

Personalised recommendations