The Military Relevance of Face Composite Tissue Allotransplantation and Regenerative Medicine Research
Maxillofacial battle injuries created the need for plastic and maxillofacial reconstructive surgery during World War I (WWI). Devastating maxillofacial injuries challenged the surgical professions to provide form and function to the defects inflicted by penetrating trauma on the battlefield. Local, regional, and distant flap transfers were developed to treat maxillofacial battle injuries in WWI and while still valued procedures, multiple surgical steps, donor site morbidity and limited esthetic-functional outcomes are often the result. During the 1980s, the advent of microsurgery added an invaluable tool to the reconstructive surgeons’ armamentarium. However, despite significant technical advances, the results following major traumatic war injuries are less than satisfactory, both esthetically and functionally. Facial allotransplantation may offer an invaluable alternative to traditional reconstructive options.
KeywordsService Member Negative Pressure Wound Therapy Facial Defect Maxillofacial Injury Composite Tissue
Ear, Nose, and Throat
Institute of Surgical Research
Negative pressure wound therapy
Oral and Maxillofacial Surgeons
World War I
The opinions or assertions contained herein are the private view of the author and should not be construed as official or reflecting the views of the Department of Defense or the US Government; the author is an employee of the US Government.
All photographs courtesy of COL Robert G Hale.
- 1.Beebe GW, DeBakey ME. Location of hits and wounds. In: Battle Casualties. Springfield: Charles C. Thomas; 1952:165-205.Google Scholar
- 2.Santoni-Ruigi P, Sykes PJ. History of Plastic Surgery. Heidelberg: Springer; 2007.Google Scholar
- 4.Sikes JW, Ghali GE. Lip cancer. In: Miloro M, ed. Peterson’s Principles of Oral and Maxillofacial Surgery. Vol. 1. Chapter 34. Hamilton, Ontario, Canada: BC Decker; 2004.Google Scholar
- 14.Jones NF, Johnson JT, Shestak KC, et al. Microsurgical reconstruction of the head and neck: interdisciplinary collaboration between head and neck surgeons and plastic surgeons in 305 cases. Ann Plast Surg. 1996;36:36-43.Google Scholar