The Spanish Experience With Face Transplantation

  • Pedro C. Cavadas
  • Luis Landin
  • Javier Ibañez
  • Alessandro Thione
  • Jose Rodrigo
  • Federico Castro
  • Marino Blanes
  • Jose Maria Zarzalejos Andes


Herein, the first composite mandible–tongue lower face transplantation in humans is reported. The procedure was performed on an HIV-positive recipient who had suffered an epidermoid carcinoma of the tongue complicated by mandibular radionecrosis and multiple flap failure. We observed incipient return of function, as demonstrated by clinical exploration and electromyography. The early postoperative course was complicated by the presence of retromandibular abscesses that were controlled successfully. No episodes of rejection have been observed so far. It is still too early to report whether the procedure allowed the patient to return to a normal social life.


Human Immunodeficiency Virus Free Flap Mycophenolate Mofetil Epidermoid Carcinoma Inferior Alveolar Nerve 
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Copyright information

© Springer London 2011

Authors and Affiliations

  • Pedro C. Cavadas
    • 1
  • Luis Landin
  • Javier Ibañez
  • Alessandro Thione
  • Jose Rodrigo
  • Federico Castro
  • Marino Blanes
  • Jose Maria Zarzalejos Andes
  1. 1.Department of Plastic and Reconstructive SurgeryClínica CavadasValenciaSpain

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