Abstract
Herein, the first composite mandible–tongue lower face transplantation in humans is reported. The procedure was performed on an HIV-positive recipient who had suffered an epidermoid carcinoma of the tongue complicated by mandibular radionecrosis and multiple flap failure. We observed incipient return of function, as demonstrated by clinical exploration and electromyography. The early postoperative course was complicated by the presence of retromandibular abscesses that were controlled successfully. No episodes of rejection have been observed so far. It is still too early to report whether the procedure allowed the patient to return to a normal social life.
Disclosure: There are no sources of support that require acknowledgment. The authors have no financial or personal relationships with other people or organizations that could influence this work inappropriately. The authors have no financial interest in any of the drugs mentioned in this work. Basiliximab, tacrolimus, sirolimus, and mycophenolate mofetil were used off-label to prevent face allograft rejection.
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Cavadas, P.C. et al. (2011). The Spanish Experience With Face Transplantation. In: Siemionow, M. (eds) The Know-How of Face Transplantation. Springer, London. https://doi.org/10.1007/978-0-85729-253-7_34
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